MGMT Gene Test: Your Key to Personalised Brain Cancer Treatment
Facing a brain cancer diagnosis can feel overwhelming, but understanding your genetic profile provides the clarity and direction needed for effective treatment. The MGMT gene test offers hope and precision in your cancer journey, helping your medical team determine the most suitable treatment approach specifically for you.
Understanding the MGMT Gene Test
The MGMT (Methylguanine Methyltransferase) gene test is a specialised genetic analysis that examines the methylation status of the MGMT gene promoter. This isn’t just another test – it’s a crucial piece of information that directly influences your treatment success.
When the MGMT gene is methylated (switched off), certain chemotherapy drugs like temozolomide work more effectively because your body’s natural repair mechanisms are less active. This knowledge allows your oncologist to create a treatment plan tailored to your unique genetic makeup.
Who Should Consider This Test?
This test is particularly important for:
- Patients newly diagnosed with glioblastoma or other high-grade gliomas
- Individuals considering chemotherapy treatment options
- Patients seeking personalised cancer treatment approaches
- Those wanting to maximise treatment effectiveness while minimising side effects
- Patients in Johannesburg, Cape Town, Durban, and across South Africa facing brain cancer decisions
Why This Test Matters for Your Health Journey
The MGMT gene test provides several critical benefits:
- Personalised Treatment: Helps your doctor choose the most effective chemotherapy regimen
- Improved Outcomes: Increases the likelihood of successful treatment response
- Reduced Side Effects: Avoids ineffective treatments and unnecessary side effects
- Peace of Mind: Provides clarity and confidence in your treatment decisions
- Time-Sensitive Information: Delivers results within 13 working days for prompt treatment planning
Understanding Your Results
Your test results will clearly indicate whether your MGMT gene promoter is methylated or unmethylated:
- Methylated Result: Indicates that certain chemotherapy drugs may be more effective for your treatment
- Unmethylated Result: Suggests alternative treatment approaches may be more beneficial
Your oncologist will explain these results in detail and discuss how they impact your specific treatment plan. Remember, this information empowers you and your medical team to make the best decisions for your health.
Affordable Precision Medicine for South Africans
| Test Option | Regular Price | Special Price | Savings |
|---|---|---|---|
| MGMT Gene Test | ZAR 26,700 | ZAR 20,000 | ZAR 6,700 |
This investment in precise diagnostics can save you from ineffective treatments and provide the clarity needed for successful cancer management.
Test Details & Preparation
- Turnaround Time: Sample received Monday by 11 am; Report in 13 working days
- Sample Types: Blood, Buccal Swab, or Plasma
- Method: Advanced PCR Technology
- Preparation: Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory
- Specialty: Oncologist-recommended testing
Why Trust Oracle Genomics?
We understand that genetic testing requires absolute confidence in accuracy and reliability. That’s why we provide:
- Nationwide Coverage: Accessible testing across South Africa including Johannesburg, Cape Town, Durban, and Pretoria
- Medical Expertise: Tests conducted by specialised oncology laboratories
- Accuracy Guarantee: Advanced PCR technology ensures precise results
- Patient Support: Clear explanations and guidance throughout the process
- Timely Results: Consistent 13-working-day turnaround for treatment planning
Take Control of Your Cancer Treatment Today
Don’t leave your treatment success to chance. The MGMT gene test provides the genetic insight needed for effective, personalised cancer care.
Book your test now while the special price of ZAR 20,000 is available!
Contact us today to schedule your test or speak with our genetic counselling team. Early genetic information can make all the difference in your treatment journey.
Available at our facilities in Johannesburg, Cape Town, Durban, Pretoria, and nationwide.

