Find Clarity About Your Blood Health with MPN Extended Profile Testing
When your blood tests show unexplained abnormalities or you’re experiencing persistent fatigue, bruising, or itching, the uncertainty can be overwhelming. The Myeloproliferative Neoplasia (MPN) Extended Profile Test provides the definitive answers you need to understand what’s happening in your body and take control of your health journey.
Understanding Your MPN Extended Profile Test
This comprehensive genetic test analyses five critical markers that help identify myeloproliferative neoplasms – a group of blood disorders where your bone marrow produces too many blood cells. Using advanced Real Time PCR and Sequencing technology, we examine:
- JAK2 V617F mutation – The most common genetic change in MPN conditions
- JAK2 Exon 12 mutations – Additional JAK2 variations that can cause similar conditions
- BCR-ABL PCR Qualitative – Detects the Philadelphia chromosome associated with certain blood cancers
- CALR mutations – Important for diagnosing essential thrombocythemia and myelofibrosis
- MPL mutations – Another key genetic marker for MPN diagnosis
Our certified laboratory technicians ensure 99% accuracy in detecting these critical genetic changes, giving you and your doctor the reliable information needed for proper diagnosis and treatment planning.
Who Should Consider This MPN Test?
If you’re experiencing any of these symptoms or circumstances, this test could provide crucial answers:
- Unexplained fatigue that doesn’t improve with rest
- Easy bruising or bleeding without obvious cause
- Persistent itching, especially after warm showers
- Night sweats or unexplained fever
- Bone pain or discomfort in your left upper abdomen
- Abnormal blood counts showing high red cells, white cells, or platelets
- Family history of blood disorders or blood cancers
- Previous abnormal bone marrow biopsy results
Many South Africans initially dismiss these symptoms as stress or normal aging, but early detection of MPN conditions can significantly improve treatment outcomes and quality of life.
Why Early MPN Detection Matters for Your Health
Getting the right diagnosis early can transform your health journey:
- Peace of Mind: End the uncertainty about your symptoms and blood results
- Targeted Treatment: Receive the specific medications that work for your genetic profile
- Disease Monitoring: Establish baseline measurements to track treatment effectiveness
- Complication Prevention: Reduce risk of blood clots, strokes, and disease progression
- Family Planning: Understand potential genetic risks for your children
- Improved Quality of Life: Better symptom management and reduced treatment side effects
Our patients across Johannesburg, Cape Town, Durban, and Pretoria consistently report feeling empowered once they have clear diagnostic information to guide their healthcare decisions.
Understanding Your Test Results
We know waiting for results can be anxiety-provoking, which is why we provide:
- Clear, Easy-to-Understand Reports: Your results come with plain language explanations
- Quick Turnaround: Samples received by Monday 9 AM get results by Saturday
- Expert Consultation: Our hematology specialists are available to explain findings
- Doctor-Ready Documentation: Comprehensive reports your physician can immediately use
- Next-Step Guidance: Clear recommendations for follow-up care and monitoring
Whether your results show no mutations detected or identify specific genetic changes, you’ll have the information needed to make informed decisions with your healthcare team.
Affordable, Life-Changing Diagnostic Testing
| Test Option | Regular Price | Special Price | Savings |
|---|---|---|---|
| MPN Extended Profile Test | R5,350 | R2,000 |
Considering the cost of ongoing symptoms, multiple doctor visits, and potential complications, this comprehensive test represents exceptional value for definitive diagnostic information.
Why Trust Oracle Genomics with Your Health?
- Nationwide Coverage: Accessible testing centres across Johannesburg, Cape Town, Durban, Pretoria and throughout South Africa
- Medical Expertise: Tests supervised by certified hematologists and oncologists
- Laboratory Excellence: SANAS-accredited facility with 99% accuracy rates
- Patient-Centred Care: Empathetic support throughout your testing journey
- Proven Track Record: Thousands of satisfied patients across South Africa
- Comprehensive Support: From sample collection to result explanation
Take the First Step Toward Clarity Today
Don’t let uncertainty about your blood health continue to cause anxiety. With convenient locations across South Africa and expert support every step of the way, getting definitive answers has never been easier.
Sample Requirements: 8 mL (4 mL minimum) whole blood in 2 Lavender top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Limited Time Special: Save R2,000 on your MPN Extended Profile Test. Early detection leads to better outcomes – don’t delay getting the answers you deserve.

