Understanding Your Leukaemia Risk: The PML-RARA Gene Rearrangement Test
When you’re facing concerns about leukaemia symptoms or need monitoring after treatment, having clear answers becomes your top priority. We understand the anxiety that comes with these health uncertainties, which is why our PML-RARA Gene Rearrangement Test provides the precise, reliable information you need to make informed decisions about your health journey.
What This Test Detects
The PML-RARA Gene Rearrangement Test is a highly specific genetic test that identifies the unique chromosomal abnormality responsible for Acute Promyelocytic Leukaemia (APL). This test uses advanced Real-Time PCR technology to detect the fusion of the PML and RARA genes, which is the hallmark genetic change in APL. Unlike general blood tests, this targeted approach provides definitive answers about this specific type of leukaemia.
Who Should Consider This Test
This test is particularly important if you’re experiencing:
- Unexplained bruising or bleeding that concerns you
- Persistent fatigue that doesn’t improve with rest
- Frequent infections or unusual susceptibility to illness
- Bone pain or discomfort that worries you
- Unexplained weight loss or loss of appetite
- Monitoring APL treatment response and remission status
- Family history of leukaemia or blood disorders
If you’ve been diagnosed with APL previously, this test becomes essential for monitoring your treatment response and detecting any potential relapse early.
Why Early Detection Matters for Your Health
Early detection of Acute Promyelocytic Leukaemia can significantly improve treatment outcomes and quality of life. When identified early, APL has become one of the most treatable forms of leukaemia with modern targeted therapies. This test provides:
- Peace of mind through definitive answers about your APL status
- Early intervention opportunities when treatment is most effective
- Treatment monitoring to ensure your therapy is working
- Relapse detection before symptoms reappear
- Personalised treatment planning based on your specific genetic profile
Understanding Your Results
We know waiting for test results can be stressful. Our team provides clear, easy-to-understand reports with expert guidance:
- Positive Result: Indicates the presence of the PML-RARA gene rearrangement, confirming APL diagnosis or indicating relapse
- Negative Result: No PML-RARA rearrangement detected, providing reassurance about APL status
- Quantitative Monitoring: For patients in treatment, we track the level of rearrangement to monitor treatment response
Every result comes with professional interpretation and next-step recommendations from our experienced oncology specialists.
Transparent Pricing – Exceptional Value
| Test Description | Regular Price | Special Price | Savings |
|---|---|---|---|
| PML-RARA Gene Rearrangement Test | ZAR 2,500 | ZAR 1,500 |
This represents exceptional value for a specialised genetic test that provides critical information for leukaemia management.
Why Trust Oracle Genomics
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Accuracy: Real-Time PCR technology ensures 99%+ accuracy in detection
- Rapid Results: Sample submission Monday/Wednesday/Friday by 9am, results available Tuesday/Thursday/Saturday
- Professional Expertise: Our oncology specialists have years of experience in genetic testing
- Patient-Focused Care: We prioritise your comfort and understanding throughout the testing process
Sample Requirements
To ensure accurate results, please provide:
- 5 mL (3 mL minimum) whole blood from 2 Lavender Top (EDTA) tubes
- Samples must be shipped refrigerated – DO NOT FREEZE
- Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory
Take Control of Your Health Today
Don’t let uncertainty about leukaemia symptoms create unnecessary anxiety. Early detection provides the best opportunity for successful treatment and peace of mind.
Limited Time Special: Book now to secure your test at the special price of ZAR 2,500 – saving you ZAR 1,500 off the regular price. This offer provides exceptional value for a test that could significantly impact your health outcomes.
Our team is ready to support you through every step of your testing journey, from initial consultation to result explanation and next-step guidance.
