Understanding Your Risk for Familial ALS: The MATR3 Gene Test
When ALS runs in your family, the uncertainty can feel overwhelming. You might wonder if you’ll develop symptoms, when they might appear, or what you can do to protect your health. Our MATR3 Gene Amyotrophic Lateral Sclerosis Type 21 NGS Genetic DNA Test provides the answers you need to take control of your health journey. For South African families concerned about inherited neurological conditions, this test offers clarity, peace of mind, and the opportunity for proactive health management.
What This Test Detects
The MATR3 gene test specifically looks for mutations associated with Amyotrophic Lateral Sclerosis Type 21, a hereditary form of motor neuron disease. Using advanced Next Generation Sequencing (NGS) technology, we analyse your DNA with exceptional precision to identify any variations in the MATR3 gene that could increase your risk of developing this condition. This isn’t just about getting results – it’s about understanding your genetic blueprint and what it means for your neurological health.
Who Should Consider This Test?
This test is particularly important if you experience:
- Family history of ALS or motor neuron disease
- Unexplained muscle weakness or twitching
- Progressive difficulty with speech or swallowing
- Concerns about passing genetic conditions to children
- Multiple family members with neurological symptoms
Many South Africans with family connections to Johannesburg, Cape Town, and Durban find this test invaluable for understanding their genetic inheritance and making informed health decisions.
Why Early Detection Matters for Your Health
Knowing your MATR3 gene status provides several crucial benefits:
- Proactive Health Management: Early awareness allows for monitoring and potential interventions
- Family Planning Confidence: Make informed decisions about starting a family
- Reduced Anxiety: Replace uncertainty with knowledge and a clear action plan
- Access to Specialist Care: Connect with neurologists who understand genetic ALS
- Clinical Trial Eligibility: Potentially qualify for emerging treatments and research
Understanding Your Test Results
We know waiting for genetic results can be stressful. That’s why we provide comprehensive support throughout the process:
- Clear, Understandable Reports: Your results come with plain-language explanations
- Genetic Counselling Session: Included with your test to help interpret findings
- Family Pedigree Analysis: We map your family history to provide context
- Next Steps Guidance: Practical recommendations based on your results
- Ongoing Support: Access to our team for any follow-up questions
Whether your results show increased risk or provide reassurance, you’ll have the guidance needed to move forward confidently.
Transparent Pricing & Value
| Service | Regular Price | Special Price |
|---|---|---|
| MATR3 ALS Type 21 NGS Test | ZAR 6,700 | |
| Genetic Counselling Session | INCLUDED | |
| Family Pedigree Analysis | INCLUDED | |
| Results Interpretation | INCLUDED | |
Turnaround Time: 3 to 4 weeks
Sample Type: Blood, Extracted DNA, or One drop Blood on FTA Card
Why Trust Oracle Genomics?
As South Africa’s leading genetic testing provider, we combine medical excellence with compassionate care:
- Nationwide Coverage: Accessible testing across Johannesburg, Cape Town, Durban, Pretoria and beyond
- Neurology Specialist Partnership: Working with leading South African neurologists
- Advanced NGS Technology: State-of-the-art sequencing for maximum accuracy
- Patient-First Approach: We understand the emotional journey of genetic testing
- Complete Confidentiality: Your genetic information is protected with the highest security standards
Take the First Step Toward Clarity
Don’t let uncertainty about familial ALS control your future. With our special pricing of ZAR 6,700, accessing this life-changing information has never been more affordable. Thousands of South African families have found peace of mind through genetic testing – you can too.
Limited Time Offer: This special pricing of ZAR 6,700 (regularly ZAR 9,350) won’t last forever. Secure your test today and take control of your neurological health journey.

