Understanding Mitochondrial Complex I Deficiency
When your body’s energy production system isn’t working properly, it can feel like you’re constantly running on empty. Mitochondrial Complex I deficiency affects how your cells generate energy, leading to symptoms that often go undiagnosed for years. Many South Africans with unexplained fatigue, muscle weakness, or neurological symptoms find themselves visiting multiple specialists without getting clear answers.
What This Test Detects
The NDUFS2 Gene Test specifically looks for mutations in the NDUFS2 gene, which plays a crucial role in your mitochondria – the powerhouses of your cells. When this gene isn’t functioning correctly, it can cause Complex I deficiency, disrupting your body’s ability to produce energy efficiently. This can manifest as neurological problems, muscle weakness, developmental delays, or other systemic issues.
Who Should Consider This Test?
If you or your child experience any of these symptoms, this test could provide the answers you’ve been seeking:
- Unexplained muscle weakness or fatigue
- Neurological symptoms without clear diagnosis
- Developmental delays in children
- Family history of mitochondrial disorders
- Multiple organ system involvement
- Exercise intolerance that seems disproportionate
Why Early Detection Matters for Your Health
Getting a definitive diagnosis through genetic testing can be life-changing. Understanding the specific genetic cause of your symptoms means:
- Targeted treatment approaches rather than trial-and-error
- Better management of symptoms and quality of life
- Understanding inheritance risks for family planning
- Peace of mind from having a clear diagnosis
- Access to appropriate specialist care and support
Understanding Your Results
Our comprehensive genetic counselling session helps you understand what your results mean for your health and your family. We explain the findings in clear, understandable language and discuss:
- What the genetic mutation means for your health
- Management strategies and treatment options
- Potential implications for other family members
- Next steps for your healthcare journey
Transparent Pricing – No Hidden Costs
| Service | Price |
|---|---|
| Regular Price | ZAR 9,350 |
| Special Price | ZAR 6,700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or Blood on FTA Card |
Why Trust Oracle Genomics?
With testing centres across South Africa including Johannesburg, Cape Town, Durban, and Pretoria, we bring world-class genetic testing to your doorstep. Our partnership with neurologists ensures your results are interpreted by specialists who understand mitochondrial disorders.
Nationwide Coverage
No matter where you are in South Africa, accessible genetic testing is available. Our network of collection centres makes getting tested convenient and stress-free.
Take Control of Your Health Today
Don’t let unexplained symptoms control your life. Early detection through genetic testing can provide the answers you need to move forward with confidence. Our team is ready to support you through every step of the process, from initial consultation to understanding your results.
Book your NDUFS2 Gene Test today and start your journey toward clarity and better health management.
