Find Clarity for Unexplained Eye Muscle Weakness
When your eyelids droop unexpectedly or your eye movements become limited, it’s natural to feel concerned about your vision and overall health. Progressive external ophthalmoplegia can significantly impact your quality of life, making everyday activities challenging. At Oracle Genomics, we understand the anxiety that comes with unexplained symptoms and provide the definitive answers you deserve through our advanced TWNK gene testing.
Understanding Your TWNK Gene Test
This specialised genetic test examines the TWNK gene using Next-Generation Sequencing (NGS) technology to identify mutations that cause progressive external ophthalmoplegia with mitochondrial DNA deletions. Think of it as reading your genetic blueprint to understand why your eye muscles may be weakening over time. The test specifically looks for autosomal dominant inheritance patterns, meaning the condition can be passed from one generation to the next with a 50% chance of transmission.
Our advanced NGS technology provides comprehensive analysis of your genetic makeup, ensuring accurate detection of even subtle mutations that might be missed by conventional testing methods.
Who Should Consider This Test?
This test is particularly important if you experience:
- Progressive limitation of eye movements in all directions
- Drooping eyelids (ptosis) that worsens over time
- Family history of similar eye movement disorders
- Unexplained muscle weakness around the eyes
- Difficulty with coordinated eye movements
- Vision changes related to eye positioning
Many South Africans initially attribute these symptoms to fatigue or aging, but when they persist or worsen, genetic testing becomes essential for proper diagnosis and management.
Why Early Detection Matters for Your Health
Receiving a definitive diagnosis through genetic testing provides numerous benefits:
- Personalised Treatment Plans: Your neurologist can develop targeted management strategies based on your specific genetic profile
- Family Planning Guidance: Understand inheritance patterns and make informed decisions about family planning
- Proactive Monitoring: Early detection allows for regular monitoring and intervention before significant complications develop
- Peace of Mind: Replace uncertainty with clarity about your condition and prognosis
- Access to Support: Connect with appropriate support groups and resources for genetic eye disorders
Understanding Your Test Results
We understand that waiting for genetic test results can be anxiety-provoking. Our team provides clear, compassionate explanation of your results:
- Positive Result: Indicates a TWNK gene mutation is present. Our genetic counsellors will explain what this means for your health and connect you with appropriate specialists
- Negative Result: No TWNK gene mutation detected, which may help rule out this specific form of progressive external ophthalmoplegia
- Uncertain Variant: Occasionally, we identify genetic changes of uncertain significance. Our experts will guide you through the implications and next steps
Every result includes a comprehensive consultation with our genetic specialists to ensure you fully understand the findings and their implications for your health.
Transparent Pricing – Exceptional Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| TWNK Gene Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
Test Details:
- Turnaround Time: 3-4 weeks
- Sample Type: Blood, Extracted DNA, or One drop Blood on FTA Card
- Preparation: Clinical history and genetic counselling session to create family pedigree chart
- Specialty: Neurology
- Method: NGS Technology
Consider the value: Early detection can prevent years of uncertainty and potentially more expensive diagnostic procedures down the line.
Why Trust Oracle Genomics?
We’ve built our reputation on accuracy, compassion, and accessibility:
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and throughout South Africa
- Medical Expertise: Collaboration with leading neurologists and genetic specialists
- Advanced Technology: State-of-the-art NGS technology for unparalleled accuracy
- Genetic Counselling: Comprehensive pre- and post-test counselling included
- Patient-Centred Care: We prioritise your comfort and understanding throughout the process
Take the First Step Toward Clarity
Don’t let uncertainty about your eye health continue to affect your quality of life. Our special pricing of ZAR 6,700 makes this essential testing more accessible than ever.
Limited Time Offer: This special pricing of ZAR 6,700 (save ZAR 2,650) won’t last forever. Secure your testing now and take control of your eye health journey.
Available at our centres in Johannesburg, Cape Town, Durban, Pretoria and nationwide. Convenient sample collection options to suit your needs.
