Understanding Hereditary Spastic Paraplegia: Your Path to Clarity Starts Here
When neurological conditions run in your family, the uncertainty can feel overwhelming. You may be watching loved ones struggle with mobility issues, wondering if you or your children might face similar challenges. The PLP1 Gene SPG2 NGS Genetic DNA Test offers the clarity you need to make informed decisions about your family’s health future.
What This Test Reveals About Your Genetic Health
The PLP1 gene plays a crucial role in producing proteins essential for healthy nerve function. When mutations occur in this gene, they can lead to SPG2 (spastic paraplegia type 2), a progressive condition that affects mobility and coordination. Our advanced Next-Generation Sequencing (NGS) technology examines your PLP1 gene with exceptional precision, identifying even the smallest genetic variations that could impact your neurological health.
Unlike basic genetic screenings, our comprehensive analysis provides detailed insights that help neurologists develop targeted management strategies for affected individuals and informed family planning guidance for those at risk.
Is This Test Right for You or Your Family?
Consider the PLP1 Gene SPG2 test if you or your family members experience:
- Progressive stiffness and weakness in the legs
- Difficulty with walking and coordination that worsens over time
- Family history of similar mobility challenges across generations
- Concerns about passing neurological conditions to children
- Unexplained spasticity or muscle tightness
- Early signs of gait abnormalities in children or young adults
Many South African families find peace of mind through genetic testing, especially when neurological conditions appear in multiple relatives. Early detection can significantly improve quality of life through timely interventions.
Why Early Detection Matters for Your Family’s Future
Knowing your genetic status empowers you to take control of your health journey. With PLP1 Gene SPG2 testing, you gain:
- Clarity for Family Planning: Make informed decisions about having children with understanding of inheritance patterns
- Early Intervention Opportunities: Begin appropriate therapies and management strategies before significant symptoms develop
- Reduced Diagnostic Uncertainty: End years of searching for answers about neurological symptoms
- Personalised Healthcare: Work with neurologists to create tailored treatment plans based on your specific genetic profile
- Emotional Peace: Replace anxiety with knowledge and a clear path forward
Understanding Your Results: We’re Here to Guide You
Receiving genetic test results can feel daunting, but you won’t face this journey alone. Our certified genetic counsellors provide comprehensive support:
- Pre-test Genetic Counselling: We help map your family history and explain what the test can reveal
- Clear Result Interpretation: Your report comes with easy-to-understand explanations of findings
- Post-test Support: We connect you with neurological specialists and resources based on your results
- Family Guidance: Help understanding what results mean for relatives and future generations
Whether your results show a mutation or provide reassuring clarity, we ensure you have the knowledge and support to move forward confidently.
Transparent Pricing – Investing in Your Family’s Health Future
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| PLP1 Gene SPG2 NGS Genetic DNA Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
| Includes genetic counselling session, comprehensive analysis, and detailed report | |||
Test Details:
- Turnaround Time: 3-4 weeks
- Sample Type: Blood, Extracted DNA, or One drop Blood on FTA Card
- Preparation: Clinical history and genetic counselling session to create family pedigree
- Method: Next-Generation Sequencing (NGS) Technology
Why South Africans Trust Oracle Genomics
Nationwide Accessibility
Convenient testing locations across Johannesburg, Cape Town, Durban, Pretoria and throughout South Africa
Expert Genetic Team
Certified genetic counsellors and neurological specialists guiding your journey
Advanced Technology
State-of-the-art NGS technology ensuring 99.9% accuracy in genetic analysis
Comprehensive Support
From initial consultation to result interpretation and specialist referrals
Take the First Step Toward Genetic Clarity Today
Don’t let uncertainty about hereditary neurological conditions dictate your family’s future. With our special pricing of ZAR 6,700, now is the perfect time to gain the knowledge that could transform your health journey.
Your genetic journey matters to us. At Oracle Genomics, we combine medical excellence with compassionate care, ensuring you feel supported every step of the way. Take control of your family’s neurological health today.

