Understanding Your Risk for Hereditary Spastic Paraplegia
If you or your loved ones are experiencing progressive walking difficulties, muscle stiffness, or have a family history of neurological conditions, the VPS37A Gene SPG53 NGS Genetic DNA Test provides the clarity you need. We understand the anxiety that comes with unexplained symptoms and family health patterns – that’s why we’ve created this comprehensive genetic analysis to give you definitive answers about your SPG53 risk.
What This Test Reveals About Your Health
The VPS37A Gene SPG53 test uses advanced Next-Generation Sequencing (NGS) technology to examine specific mutations in the VPS37A gene that cause hereditary spastic paraplegia type 53. This isn’t just another genetic test – it’s a precise diagnostic tool that identifies the exact genetic variations responsible for this progressive neurological condition that affects mobility and coordination.
Our test provides comprehensive analysis of the entire VPS37A gene, detecting even the smallest mutations that could impact your neurological health. This level of detail ensures you receive the most accurate genetic information available, giving you and your healthcare team the foundation for informed decision-making.
Is This Test Right for You or Your Family?
This genetic test is particularly important if you’re experiencing:
- Progressive difficulty walking or maintaining balance
- Muscle stiffness or spasticity in your legs
- Family history of similar neurological symptoms
- Unexplained coordination problems that began in childhood or early adulthood
- Concerns about passing genetic conditions to your children
Many South African families face these challenges without clear answers. Our test provides the genetic clarity needed to understand your condition and plan for the future.
Why Early Detection Matters for Your Mobility
Knowing your genetic status for SPG53 provides several crucial health benefits:
- Early Intervention: Identify risk before significant symptoms develop, allowing for proactive management
- Family Planning: Make informed decisions about having children with reduced genetic risk
- Personalised Treatment: Work with neurologists to create targeted management strategies
- Peace of Mind: Eliminate uncertainty about your genetic risk for hereditary spastic paraplegia
- Future Planning: Prepare for potential mobility challenges with confidence and support
Understanding Your Genetic Results
We know waiting for genetic results can be stressful. That’s why we provide comprehensive genetic counselling both before and after your test. Your results will clearly indicate whether VPS37A gene mutations associated with SPG53 are present, and our medical team will explain exactly what this means for your health.
Positive results don’t mean certain disease development – they provide valuable information for monitoring and management. Negative results offer significant relief and clarity. Either way, you’ll have the knowledge to make empowered healthcare decisions.
Transparent Pricing – Exceptional Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| VPS37A SPG53 NGS Genetic Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
| Genetic Counselling Session | Included at no extra cost | ||
| Family Pedigree Analysis | Included in comprehensive service | ||
Considering the lifelong impact of neurological conditions, this investment in your health provides exceptional value and peace of mind.
Why Thousands of South Africans Trust Oracle Genomics
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise: Tests supervised by qualified neurologists and genetic specialists
- 99.9% Accuracy: Advanced NGS technology ensures reliable results you can trust
- Comprehensive Support: Genetic counselling included to help you understand your results
- Rapid Turnaround: Results typically available within 3-4 weeks
- Multiple Sample Options: Blood, extracted DNA, or simple blood spot on FTA card
Take the First Step Toward Genetic Clarity Today
Don’t let uncertainty about hereditary spastic paraplegia control your future. With our special pricing of only ZAR 6,700, there’s never been a better time to gain the genetic insight you need.
Book Your Test Now: Call 0861 UBUNTU (82688) or visit our website to schedule your genetic counselling session and testing.
Walk-in Appointments Available at our centres in major cities including Johannesburg, Cape Town, Durban and Pretoria.
Early detection could preserve your mobility and quality of life. Take control of your neurological health with confidence.

