Understanding Your Genetic Risk for Amelogenesis Imperfecta
If you or your family members experience abnormal tooth development, discoloured teeth, or severe dental enamel problems, you may be dealing with Amelogenesis Imperfecta – a genetic condition that affects how tooth enamel forms. The C4orf26 Gene Amelogenesis Imperfecta Type 2A4 NGS Genetic DNA Test provides the clarity you need to understand your genetic risk and take control of your dental health.
What This Test Detects
The C4orf26 gene plays a crucial role in proper tooth enamel formation. When mutations occur in this gene, it can lead to Amelogenesis Imperfecta type 2A4 – a hereditary condition characterised by abnormal enamel development. Our advanced Next Generation Sequencing (NGS) technology examines your DNA to identify specific mutations in the C4orf26 gene, providing definitive answers about your genetic risk for this dental disorder.
Who Should Consider This Test
This genetic test is particularly important if you or your family members experience:
- Abnormal tooth enamel development from childhood
- Discoloured teeth (yellow, brown, or grey appearance)
- Teeth that appear small or misshapen
- Increased tooth sensitivity or pain
- Early and severe tooth decay despite good oral hygiene
- Family history of similar dental problems
- Planning pregnancy with family history of enamel disorders
Why Genetic Testing Matters for Your Dental Health
Early detection through genetic testing provides significant benefits:
- Proactive Dental Care: Knowing your genetic risk allows for early intervention and specialised dental treatments
- Family Planning Confidence: Understand inheritance patterns for informed family decisions
- Peace of Mind: Eliminate uncertainty about the cause of dental problems
- Personalised Treatment: Guide dental professionals in creating targeted treatment plans
- Cost Savings: Prevent extensive dental work through early management
Understanding Your Test Results
Our comprehensive genetic counselling ensures you fully understand your results:
- Positive Result: Indicates a C4orf26 gene mutation associated with Amelogenesis Imperfecta. Our genetic counsellors will explain what this means for your dental health and family planning
- Negative Result: No mutation detected in the C4orf26 gene, suggesting other causes for dental concerns
- Variant of Unknown Significance: Rare genetic changes where more research is needed – we provide ongoing support and monitoring
All results include detailed explanations and recommendations for next steps with dental specialists.
Transparent Pricing – Exceptional Value
| Test Description | Regular Price | Special Price | Turnaround Time |
|---|---|---|---|
| C4orf26 Gene Amelogenesis Imperfecta Type 2A4 NGS Genetic DNA Test | ZAR 6,700 | 3-4 Weeks |
Price includes comprehensive genetic analysis, detailed report, and genetic counselling session
Why Trust Oracle Genomics
- Nationwide Coverage: Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Genetic Counselling: Every test includes professional genetic counselling to create your family pedigree chart
- Advanced NGS Technology: Latest Next Generation Sequencing for maximum accuracy
- Multiple Sample Options: Blood, extracted DNA, or simple blood spot on FTA card
- Dermatology Specialist Partnership: Working with leading dermatologists for comprehensive care
- Complete Preparation Support: We guide you through clinical history documentation and genetic counselling
Take Control of Your Dental Health Today
Don’t let uncertainty about hereditary dental conditions affect your quality of life. Early genetic testing can provide the answers you need for proactive dental care and informed family planning decisions.
Limited Time Special: Save ZAR 2,650 on your genetic test – book now while this offer lasts!
Convenient Nationwide Access: Testing available throughout South Africa with easy sample collection options.
Your journey to understanding your genetic dental health starts with one simple decision. Contact Oracle Genomics today and take the first step toward clarity and confidence in your dental future.

