Find Answers for Unexplained Cold-Triggered Inflammation
Living with mysterious recurrent fevers, skin rashes that appear with cold exposure, or unexplained joint pain can be frightening and isolating. If you’ve been searching for answers about these puzzling symptoms that seem to run in your family, our NLRC4 Gene Cold Autoinflammatory Syndrome Type 4 test provides the clarity and certainty you deserve. We understand the emotional toll of not knowing what’s causing your symptoms, and we’re here to help you take control of your health journey with confidence.
Understanding the NLRC4 Gene Test
The NLRC4 Gene Cold Autoinflammatory Syndrome Type 4 test is a specialised genetic examination that looks for specific mutations in your NLRC4 gene. This gene plays a crucial role in regulating your body’s inflammatory response. When mutations occur, it can lead to the immune system overreacting to cold temperatures, causing the characteristic symptoms of this rare condition. Our test uses advanced Next-Generation Sequencing (NGS) technology, the gold standard in genetic testing, to provide you with the most accurate and reliable results possible.
Who Should Consider This Test?
This test is particularly important if you or your family members experience:
- Recurrent fevers that seem to occur without infection
- Skin rashes or hives triggered by cold exposure
- Joint pain and inflammation that worsens in cold weather
- Unexplained abdominal pain or gastrointestinal symptoms
- Family history of similar symptoms across generations
- Diagnosis delays despite multiple doctor visits
Many patients tell us they’ve spent years searching for answers, visiting multiple specialists without finding the root cause of their symptoms. This test can provide the missing piece to your diagnostic puzzle.
Why This Test Matters for Your Health
Getting an accurate diagnosis through our NLRC4 gene test can be life-changing. With clear results, you and your healthcare provider can:
- Develop targeted treatment strategies that address the root cause
- Reduce unnecessary medications and treatments
- Prevent complications through early intervention
- Provide peace of mind for you and your family members
- Make informed decisions about family planning
- Connect with appropriate specialists for ongoing care
Early detection means you can take proactive steps to manage your condition effectively and improve your quality of life.
Understanding Your Results
We know waiting for genetic test results can be anxiety-provoking. That’s why we provide comprehensive support throughout the process. Your results will clearly indicate whether NLRC4 gene mutations were detected, and our genetic counselling team will help you understand what this means for your health. Whether your results are positive or negative, you’ll receive personalised guidance on next steps and recommendations for follow-up care with appropriate specialists.
Remember: A positive result doesn’t mean you’re destined to suffer. It means you now have the information needed to take control of your health with targeted treatments and lifestyle adjustments.
Transparent Pricing – Excellent Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| NLRC4 Gene Test | R6,700 | R2,650 |
Turnaround Time: 3-4 weeks
Sample Type: Blood, Extracted DNA, or One drop Blood on FTA Card
Includes: Genetic counselling session and family pedigree analysis
Considering the cost of ongoing specialist visits, unnecessary treatments, and the emotional burden of not knowing, this test represents excellent value for gaining clarity about your health.
Why Trust Oracle Genomics?
At Oracle Genomics, we combine medical expertise with genuine patient care. Our team includes specialists in genetic testing and autoinflammatory conditions, ensuring you receive the highest standard of care. We’re proud to serve patients across South Africa, with convenient testing locations in:
- Johannesburg and surrounding areas
- Cape Town and Western Cape region
- Durban and KwaZulu-Natal
- Pretoria and Gauteng province
- Plus nationwide coverage through our partner network
Our NGS technology provides 99.9% accuracy, and every test includes professional genetic counselling to ensure you fully understand your results and their implications.
Take the First Step Toward Clarity Today
Don’t let unexplained symptoms control your life any longer. Every day without answers is another day of uncertainty. Our simple testing process and comprehensive support make it easy to get the clarity you need.
Limited Time Offer: Book within the next 7 days and receive priority processing at no extra cost. Take advantage of our special pricing while it lasts and start your journey to better health today.

