Understanding KRT6A Gene Pachyonychia Congenita Type 3
If you’re experiencing thickened, painful nails that make everyday activities difficult, or if you’ve noticed unusual skin thickening on your palms and soles, you’re not alone. Pachyonychia Congenita Type 3 is a rare genetic condition that affects nail and skin development, often causing significant discomfort and impacting quality of life. At Oracle Genomics, we understand the frustration of living with unexplained symptoms and the importance of getting accurate answers.
What This Test Detects
Our advanced NGS (Next Generation Sequencing) genetic test specifically analyses the KRT6A gene for mutations that cause Pachyonychia Congenita Type 3. This condition is characterised by thickened nails (pachyonychia), palmoplantar keratoderma (thickened skin on palms and soles), and often includes oral leukokeratosis (white patches in the mouth). The test examines the entire KRT6A gene sequence to identify any pathogenic variants that could be responsible for your symptoms.
Who Should Consider This Test
This genetic test is particularly important if you experience:
- Severely thickened, discoloured nails that are difficult to trim
- Painful calluses and blisters on palms and soles
- White patches inside your mouth (oral leukokeratosis)
- Family history of similar nail and skin conditions
- Early childhood onset of nail abnormalities
- Difficulty walking or using hands due to nail and skin changes
Why Genetic Testing Matters for Your Health
Getting an accurate genetic diagnosis provides several crucial benefits:
- Definitive Diagnosis: End the uncertainty and get clear answers about your condition
- Personalised Management: Work with your dermatologist to develop targeted treatment strategies
- Family Planning Insights: Understand inheritance patterns for future family planning
- Peace of Mind: Reduce anxiety by understanding the genetic basis of your symptoms
- Early Intervention: Implement appropriate care strategies before symptoms worsen
Understanding Your Results
We make understanding your genetic results straightforward and reassuring. Your comprehensive report will clearly indicate whether a KRT6A gene mutation was detected and provide detailed explanations in easy-to-understand language. Our genetic counsellors are available to help you interpret the results and discuss next steps with your healthcare provider. Remember, a positive result means we can develop targeted management strategies, while a negative result helps rule out this specific condition.
Pricing and Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| KRT6A Gene Test | R9,350 | R6,700 | R2,650 |
This comprehensive package includes genetic counselling, advanced NGS analysis, and detailed reporting. Considering the cost of ongoing symptomatic treatments and specialist consultations, this test represents excellent value for achieving a definitive diagnosis.
Why Trust Oracle Genomics
We bring medical excellence to genetic testing across South Africa:
- Nationwide Coverage: Available in Johannesburg, Cape Town, Durban, Pretoria and throughout South Africa
- Advanced Technology: State-of-the-art NGS technology ensures 99.9% accuracy
- Expert Team: Specialist genetic counsellors and dermatology experts
- Complete Support: From pre-test counselling to post-result guidance
- Confidential Service: Your privacy and data security are our priority
Take Control of Your Health Today
Don’t let unexplained nail and skin symptoms continue to affect your quality of life. Early genetic diagnosis can lead to better management strategies and improved outcomes. Our simple testing process requires only a blood sample or DNA extraction, with results available in 3-4 weeks.
Book your genetic counselling session today and take the first step toward understanding your genetic health. Call us now or complete our online booking form to schedule your consultation at a location convenient for you.
Limited time special pricing available. Take advantage of our R2,650 savings while you can.
