Find Clarity About Your Skin Cancer Risk with ERCC4 Gene Testing
If you or your child experiences extreme sun sensitivity, frequent sunburns, or has a family history of early skin cancers, you understand the constant worry. The ERCC4 Gene Test provides definitive answers about Xeroderma Pigmentosum Group F – a genetic condition that dramatically increases skin cancer risk from minimal sun exposure.
Understanding Your ERCC4 Gene Test
This advanced genetic test examines your ERCC4 gene using Next Generation Sequencing (NGS) technology – the gold standard in genetic analysis. The ERCC4 gene plays a crucial role in repairing DNA damage caused by ultraviolet (UV) radiation from sunlight. When this gene has mutations, your body cannot properly repair sun damage, leading to Xeroderma Pigmentosum Group F.
Our test provides:
- Comprehensive analysis of the entire ERCC4 gene
- Detection of even rare mutations
- 99.9% accuracy through NGS technology
- Clear, actionable results you can trust
Who Should Consider This Test?
This test is essential if you experience:
- Extreme sun sensitivity – severe sunburn from minimal exposure
- Frequent freckling in sun-exposed areas during childhood
- Family history of early-onset skin cancers
- Unexplained eye problems related to light sensitivity
- Developmental delays with sun sensitivity symptoms
- Multiple skin cancers before age 20
Many South African families with fair skin or mixed heritage discover this test provides life-saving insights about their sun protection needs.
Why Early Detection Matters for Your Health
Knowing your ERCC4 status empowers you to:
- Implement targeted sun protection strategies that actually work
- Reduce skin cancer risk by up to 95% with proper management
- Plan appropriate medical monitoring with dermatologists
- Make informed family planning decisions with genetic counselling
- Access specialised care through our nationwide network
- Gain peace of mind through definitive diagnosis
Understanding Your Test Results
We make understanding your results simple and reassuring:
- Positive Result: Our genetic counsellors will guide you through creating a comprehensive sun protection and monitoring plan with our network of dermatologists across South Africa.
- Negative Result: Peace of mind knowing you don’t have Xeroderma Pigmentosum Group F, though continued sun safety remains important.
- Variant of Unknown Significance: Rare cases where we find a genetic change with unclear impact – we provide ongoing monitoring and research updates.
Every result includes a detailed consultation with our genetic specialists to ensure you feel confident and supported.
Transparent Pricing – Exceptional Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| ERCC4 Gene Test | ZAR 6,700 | ZAR 2,650 | |
| Genetic Counselling Session | INCLUDED | ||
| Family Pedigree Analysis | INCLUDED | ||
| Results Consultation | INCLUDED | ||
Consider the value: Early detection could prevent thousands in future medical costs and, most importantly, save lives.
Why Trust Oracle Genomics?
- Nationwide Coverage: Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise: Partnered with leading dermatologists and genetic specialists
- Advanced Technology: NGS technology ensures 99.9% accuracy
- Complete Support: Genetic counselling included with every test
- Rapid Results: 3-4 week turnaround with ongoing support
- Multiple Sample Options: Blood, extracted DNA, or simple FTA card blood drop
Take Control of Your Skin Health Today
Don’t let uncertainty about sun sensitivity control your life. With our special pricing of ZAR 6,700, there’s never been a better time to get answers.
Your journey to clarity starts here. With Oracle Genomics, you’re not just getting a test – you’re gaining a partner in your health journey, with support available across South Africa from our teams in Johannesburg, Cape Town, Durban, and nationwide.

