Understanding Your Sun Sensitivity: POLH Gene Xeroderma Pigmentosum DNA Testing
Living with extreme sun sensitivity can be frightening and isolating. If you find yourself avoiding sunlight, experiencing painful blistering after minimal exposure, or worrying about your family’s skin cancer history, you’re not alone. Our POLH Gene Xeroderma Pigmentosum DNA Test provides the clarity you need to understand your genetic makeup and take control of your skin health.
What This Test Reveals About Your DNA
The POLH gene plays a critical role in your body’s ability to repair DNA damage caused by ultraviolet (UV) radiation. When this gene contains mutations, it leads to Xeroderma Pigmentosum variant type – a condition where your skin cannot properly repair sun damage, dramatically increasing your risk of skin cancers and other complications.
Our Next Generation Sequencing (NGS) technology examines your POLH gene with exceptional precision, identifying even the smallest genetic variations that could be affecting your health. This isn’t just a test – it’s a roadmap to understanding your unique genetic vulnerabilities.
Is This Test Right for You or Your Family?
Consider this genetic testing if you experience:
- Extreme sunburn reactions with minimal exposure
- Frequent blistering or peeling after being in sunlight
- Multiple freckles or unusual skin pigmentation changes
- Family history of early-onset skin cancers
- Diagnosis of Xeroderma Pigmentosum in relatives
- Unexplained eye sensitivity to light
- Neurological symptoms combined with sun sensitivity
Many South Africans struggle with sun-related skin issues, but when these symptoms appear in childhood or affect multiple family members, genetic testing becomes essential for proper management.
Why Early Detection Matters for Your Health
Knowing your POLH gene status transforms how you approach sun protection and skin cancer prevention:
- Personalised Protection: Tailor your sun avoidance strategies based on your genetic risk level
- Cancer Prevention: Implement targeted screening that can detect skin cancers at their earliest, most treatable stages
- Family Planning: Understand inheritance patterns for informed family decisions
- Peace of Mind: Replace uncertainty with concrete knowledge about your genetic makeup
- Treatment Guidance: Help your dermatologist create the most effective management plan
Understanding Your Test Results
We know waiting for genetic results can be anxiety-provoking. Our comprehensive reporting makes your results clear and actionable:
- Clear Interpretation: Easy-to-understand explanations of what your genetic findings mean
- Clinical Guidance: Specific recommendations for sun protection and monitoring
- Genetic Counselling: Professional support to help you understand implications for you and your family
- Next Steps: Concrete actions you can take based on your results
- Healthcare Team Coordination: We work directly with your dermatologist to ensure seamless care
Remember: A positive result doesn’t mean you’ll definitely develop complications – it means you have the knowledge to prevent them.
Transparent Pricing – Investing in Your Health
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| POLH Gene Xeroderma Pigmentosum DNA Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
| Includes genetic counselling session and comprehensive results interpretation | |||
Test Details:
- Turnaround Time: 3-4 weeks
- Sample Type: Blood, Extracted DNA, or One drop Blood on FTA Card
- Method: Advanced NGS Technology
- Specialty: Dermatology Genetics
Consider this: The cost of advanced skin cancer treatment can exceed ZAR 100,000. This test represents a smart investment in prevention.
Why Thousands of South Africans Trust Oracle Genomics
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise: Developed and interpreted by specialist dermatologists and geneticists
- Accuracy Guarantee: 99.9% detection rate using cutting-edge NGS technology
- Patient Support: Genetic counselling included to ensure you fully understand your results
- Privacy Protected: Your genetic information is handled with the highest confidentiality standards
- Proven Track Record: Thousands of successful genetic tests performed nationwide
Take Control of Your Skin Health Today
Don’t let uncertainty about your sun sensitivity control your life. With our special pricing of ZAR 6,700, there’s never been a better time to get the answers you deserve.
Limited Time Offer: This special pricing of ZAR 6,700 (regularly ZAR 9,350) won’t last forever. Every day without answers is another day of uncertainty about your skin health risks.
Early Detection Advantage: The sooner you understand your genetic risk, the sooner you can implement effective prevention strategies that could save your life.
Ready for clarity? Contact Oracle Genomics today and take the first step toward understanding your genetic skin health.

