Understanding Your Risk for Protein S Deficiency
If you’ve experienced unexplained blood clots or have family members with similar health concerns, you’re not alone. Many South Africans live with undiagnosed Protein S deficiency, unaware of their increased risk for serious clotting events. Our PROS1 Gene Protein S Deficiency test provides the clarity you need to protect your health and make informed decisions about your future.
What Does This Test Detect?
This advanced NGS (Next Generation Sequencing) genetic test specifically examines the PROS1 gene for mutations that cause Protein S deficiency. Protein S is a natural anticoagulant in your blood that helps prevent excessive clotting. When this protein is deficient due to genetic factors, your risk of developing dangerous blood clots increases significantly. The test identifies autosomal dominant inheritance patterns, meaning if one parent carries the mutation, there’s a 50% chance of passing it to each child.
Who Should Consider This Test?
This test is particularly important if you experience:
- Unexplained blood clots before age 45
- Recurrent clotting episodes without clear cause
- Family history of blood clotting disorders
- Blood clots in unusual locations (brain, abdomen, arms)
- Pregnancy-related clotting complications
- Multiple miscarriages or pregnancy losses
Why Early Detection Matters for Your Health
Knowing your genetic status empowers you to take proactive steps to prevent serious complications. Early detection of Protein S deficiency can help:
- Prevent life-threatening conditions like pulmonary embolism
- Reduce risk of stroke and heart attack
- Guide appropriate treatment during surgery or pregnancy
- Inform family members about their potential risk
- Provide peace of mind through accurate diagnosis
Understanding Your Test Results
Our genetic counsellors will guide you through your results with compassion and clarity. If a mutation is detected, we’ll explain what this means for your health and provide personalized recommendations for management and prevention. Negative results offer valuable reassurance about your clotting risk. Either way, you’ll leave with a clear understanding of your genetic profile and next steps.
Comprehensive Pricing and Value
| Service | Regular Price | Special Price |
|---|---|---|
| PROS1 Gene Protein S Deficiency Test | ZAR 9,350 | ZAR 6,700 |
| Genetic Counselling Session | Included | |
| Family Pedigree Analysis | Included | |
| Results Interpretation | Included | |
Considering the potential cost of treating blood clot complications, this test represents exceptional value for your long-term health investment.
Nationwide Trust and Accessibility
Oracle Genomics brings expert genetic testing to communities across South Africa. With collection centres in Johannesburg, Cape Town, Durban, Pretoria and nationwide, accessing this crucial health information is convenient and reliable. Our NGS technology ensures 99.9% accuracy, and our 3-4 week turnaround time means you won’t face prolonged uncertainty.
Take the Next Step Toward Clarity
Don’t let uncertainty about your clotting risk control your life. Our simple blood sample or FTA card collection makes testing straightforward and stress-free. With included genetic counselling and comprehensive result interpretation, you’ll have the support you need every step of the way.
Book your test today and take control of your health journey. Early detection could save your life.
Contact Oracle Genomics now to schedule your PROS1 Gene Protein S Deficiency test and begin your path to clarity and confidence.

