Understanding Male Infertility: The AZF Region Genetic Test
When you’re facing challenges starting a family, the uncertainty can feel overwhelming. Many couples discover that male factor infertility plays a significant role, and genetic causes like Y chromosome microdeletions in the AZF region are more common than you might think. At Oracle Genomics, we understand the emotional journey you’re on, and we’re here to provide clear, definitive answers through our advanced genetic testing.
What This Test Detects
The AZF region Y chromosome microdeletion test uses Next Generation Sequencing (NGS) technology to examine specific regions of the Y chromosome that are essential for sperm production. When these regions (AZFa, AZFb, or AZFc) have microdeletions, it can lead to azoospermia – the complete absence of sperm in semen. This isn’t about blame or fault; it’s about understanding the biological factors at play so you can make informed decisions about your fertility journey.
Who Should Consider This Test
This test is particularly important if you’re experiencing:
- Diagnosed azoospermia (no sperm in semen analysis)
- Severe oligospermia (very low sperm count)
- Unexplained male infertility despite normal hormone levels
- Family history of male infertility
- Planning assisted reproductive technologies like IVF
Many men discover these genetic factors only after extensive fertility investigations. Early testing can save time, reduce emotional stress, and guide treatment decisions more effectively.
Why This Matters for Your Health Journey
Getting clear answers about AZF microdeletions provides several important benefits:
- Treatment Guidance: Different AZF deletions have different implications for sperm retrieval success rates
- Family Planning: Understand the risk of passing genetic factors to male offspring
- Emotional Closure: Move from uncertainty to having a clear understanding of your situation
- Cost Savings: Avoid unnecessary fertility treatments that may not be effective for your specific condition
- Future Planning: Make informed decisions about donor sperm options or adoption if needed
Understanding Your Results
We know waiting for genetic test results can be anxiety-provoking. Our process is designed to provide clarity and support:
- Clear Reporting: Your results will clearly indicate whether AZF microdeletions are present
- Genetic Counselling: Included with your test to help interpret results and discuss implications
- Actionable Insights: Specific guidance on what your results mean for fertility treatment options
- No Medical Jargon: We explain everything in plain language you can understand
Remember: A positive result doesn’t mean you can’t have children – it means we can now choose the most appropriate path forward based on solid information.
Transparent Pricing – No Hidden Costs
| Service | Regular Price | Special Price |
|---|---|---|
| AZF Microdeletion Genetic Test | ZAR 9,350 | ZAR 6,700 |
| Genetic Counselling Session | INCLUDED | |
| Family Pedigree Analysis | INCLUDED | |
| Results Interpretation | INCLUDED | |
Considering the cost of multiple fertility treatments without proper diagnosis, this test represents significant potential savings and emotional relief.
Why Trust Oracle Genomics
- Nationwide Coverage: Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Advanced Technology: Using latest NGS sequencing for highest accuracy
- Medical Expertise: Specialised in reproductive genetics and male infertility
- Patient-Focused: We understand the sensitive nature of fertility testing
- Proven Accuracy: Gold standard testing methodology with reliable results
Take the First Step Toward Clarity
Don’t let uncertainty control your family planning journey. With results in 3-4 weeks and comprehensive support throughout the process, now is the time to get the answers you deserve.
Sample Collection: Simple blood draw or DNA sample at our nationwide facilities
Preparation: Bring your clinical history for comprehensive genetic counselling and family pedigree analysis