E2A (ALL) Genetic Test: Your Path to Early Leukaemia Detection
When you’re experiencing unexplained symptoms or have concerns about blood disorders, the uncertainty can be overwhelming. The E2A (ALL) genetic test provides the clarity you need to move forward with confidence. This specialised test detects specific genetic abnormalities associated with acute lymphoblastic leukaemia, giving you and your doctor critical information for making informed healthcare decisions.
Understanding the E2A (ALL) Genetic Test
The E2A (ALL) test uses advanced Fluorescence In Situ Hybridisation (FISH) technology to identify specific genetic rearrangements in the E2A gene, which are strongly associated with acute lymphoblastic leukaemia. This isn’t just another blood test – it’s a precise genetic analysis that looks deep into your cells to detect abnormalities that might indicate leukaemia development.
Using either bone marrow or peripheral blood samples, our expert laboratory team examines your genetic material with exceptional accuracy. The test specifically targets the t(1;19) translocation involving the E2A gene, which occurs in approximately 5-6% of childhood ALL cases and a smaller percentage of adult cases.
Who Should Consider This Test?
If you’re experiencing any of these symptoms, the E2A (ALL) test could provide essential answers:
- Unexplained fatigue that doesn’t improve with rest
- Frequent infections or slow recovery from illnesses
- Unexplained bruising or bleeding tendencies
- Persistent bone or joint pain
- Enlarged lymph nodes, liver, or spleen
- Abnormal blood counts showing low red cells, white cells, or platelets
- Family history of blood cancers or genetic disorders
This test is particularly important for individuals with suspected or diagnosed acute lymphoblastic leukaemia, as it helps determine specific genetic subtypes that can influence treatment choices and prognosis.
Why Early Detection Matters for Your Health
Early genetic detection of leukaemia abnormalities can significantly impact your treatment journey and outcomes:
- Personalised Treatment Planning: Knowing your specific genetic profile helps doctors tailor treatments specifically for your type of leukaemia
- Better Prognostic Information: E2A rearrangements have specific clinical implications that guide treatment intensity decisions
- Peace of Mind: Either ruling out concerning genetic changes or confirming them early provides clarity for moving forward
- Monitoring Treatment Response: The test can be used to monitor minimal residual disease during and after treatment
- Family Planning Insights: Understanding genetic factors can inform discussions about family health risks
Understanding Your Test Results
We understand that waiting for genetic test results can be anxiety-provoking. Our team provides clear, compassionate explanations of your results:
- Negative Result: No E2A gene rearrangements detected – this provides reassurance and helps rule out this specific genetic subtype of ALL
- Positive Result: E2A rearrangements detected – this information helps your healthcare team develop the most effective treatment strategy
- Comprehensive Report: You’ll receive a detailed report explaining the findings in clear language, with guidance for next steps
- Professional Support: Our genetic counsellors are available to help you understand your results and their implications
Remember: A positive result provides valuable information for targeted treatment, not a final prognosis. Many people with genetic abnormalities respond well to modern therapies.
Transparent Pricing – No Hidden Costs
| Test Option | Regular Price | Special Price | Savings |
|---|---|---|---|
| E2A (ALL) Genetic Test | ZAR 1,750 | ZAR 600 |
Turnaround Time: 3-4 days
Sample Type: Bone Marrow / Peripheral blood
Components: Sodium Heparin Vacutainer (2ml)
Consider this: Early detection of genetic abnormalities can prevent costly complications and guide more effective, targeted treatments that may ultimately save both health and financial resources.
Why Trust Oracle Genomics?
We’ve built our reputation on accuracy, compassion, and accessibility for all South Africans:
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, and Pretoria
- Expert Laboratory Team: Highly trained genetic specialists using state-of-the-art FISH technology
- Rapid Results: Most results within 3-4 days, not weeks
- Quality Assurance: Stringent quality controls ensuring result accuracy you can trust
- Patient-First Approach: Compassionate support throughout your testing journey
- Doctor Collaboration: We work closely with your healthcare providers for integrated care
Take Control of Your Health Today
Don’t let uncertainty about genetic risks delay your peace of mind. Early detection through the E2A (ALL) test provides the information you need to make empowered health decisions.
Important Note: This test requires a doctor’s prescription for most cases. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Limited Time Offer: The special price of ZAR 1,750 represents significant savings – book now to secure this rate while available.
Your health journey deserves clarity and confidence. Contact Oracle Genomics today to schedule your E2A (ALL) genetic test and take the first step toward understanding your genetic health.
Nationwide Support | Professional Excellence | Patient-Centred Care

