Understanding Your Leukaemia Risk: MLL Gene Testing for AML and ALL
When you’re facing concerns about blood disorders or leukaemia symptoms, the uncertainty can be overwhelming. We understand that waiting for answers about potential AML (Acute Myeloid Leukaemia) or ALL (Acute Lymphoblastic Leukaemia) creates significant anxiety. Our MLL gene rearrangement test provides the clarity and confidence you need during this challenging time.
What Does the MLL Gene Test Detect?
The MLL gene rearrangement test is a sophisticated genetic analysis that identifies specific abnormalities in the MLL (Mixed Lineage Leukaemia) gene. When this gene becomes rearranged or altered, it can trigger the development of aggressive forms of leukaemia, particularly AML and ALL. Using Fluorescence In Situ Hybridization (FISH) technology, we examine your bone marrow or blood samples at the chromosomal level to detect these critical genetic changes.
This isn’t just another blood test – it’s a targeted investigation into the genetic drivers of your condition, providing information that directly impacts treatment decisions and prognosis.
Who Should Consider This Test?
If you’re experiencing any of these concerning symptoms, the MLL gene test could provide essential answers:
- Unexplained fatigue and weakness that doesn’t improve with rest
- Frequent infections or slow recovery from common illnesses
- Unexplained bruising or bleeding that takes longer than normal to stop
- Persistent fever without clear cause
- Bone pain or tenderness, especially in long bones
- Unexplained weight loss despite normal eating habits
- Pale skin, shortness of breath, or dizziness
- Swollen lymph nodes in neck, armpits, or groin
This test is also crucial for patients already diagnosed with leukaemia to determine the specific genetic characteristics of their disease.
Why Early Detection Matters for Your Health
Identifying MLL gene rearrangements early can significantly impact your treatment journey and outcomes:
- Personalized Treatment Planning: MLL-positive leukaemias often require different treatment approaches than standard cases
- Prognostic Information: Understanding your genetic profile helps predict disease progression and response to therapy
- Treatment Monitoring: The test can track treatment effectiveness and detect early relapse
- Family Planning: While most MLL rearrangements are acquired (not inherited), genetic counseling may be recommended
- Peace of Mind: Either way, knowing your genetic status reduces uncertainty and empowers informed decisions
Understanding Your Test Results
We know waiting for genetic test results can be stressful. Our team provides clear, compassionate explanations of your findings:
- Positive Result: Indicates MLL gene rearrangement is present, guiding targeted treatment strategies
- Negative Result: MLL rearrangement is not detected, which may influence treatment selection
- Inconclusive Result: Rare cases may require additional testing for complete clarity
Every result comes with detailed interpretation and, when needed, recommendations for next steps. You’re never alone in understanding your results.
Transparent Pricing – No Hidden Costs
| Test Description | Regular Price | Special Price | Savings |
|---|---|---|---|
| MLL Gene Rearrangement Test (AML/ALL) | ZAR 1,750 | ZAR 600 | |
| Includes sample collection, analysis, and detailed report | |||
Turnaround Time: 3-4 business days
Sample Type: Bone Marrow / Peripheral blood
Method: FISH (Fluorescence In Situ Hybridization)
Why Trust Oracle Genomics?
Your health deserves the highest standards of care and accuracy:
- Nationwide Coverage: Accessible testing centres across Johannesburg, Cape Town, Durban, and Pretoria
- Medical Expertise: Tests conducted by qualified specialists in oncology genetics
- Advanced Technology: State-of-the-art FISH methodology for precise results
- Patient-Centred Care: We prioritize your comfort and understanding throughout the process
- Rapid Results: Quick turnaround without compromising accuracy
Take Control of Your Health Journey Today
Don’t let uncertainty about leukaemia symptoms control your life. Early detection through MLL gene testing can provide the answers you need for proper treatment and peace of mind.
Ready to get started? Contact us today to schedule your test or speak with our genetic counseling team. Remember, this test requires a doctor’s prescription (except for surgery, pregnancy, or travel abroad cases).
Limited time special pricing available. Early detection saves lives – don’t wait until symptoms worsen.

