Protect Yourself From Chemotherapy Toxicity With Our DPD Gene Test
If you’re facing 5-FU chemotherapy treatment, you deserve to know your genetic risk for severe side effects before treatment begins. Many South African patients experience unexpected, life-threatening reactions to this common chemotherapy drug – reactions that could be prevented with proper genetic screening.
Our DPD Gene Mutations Test provides the crucial information your medical team needs to create a safer, more effective treatment plan tailored specifically to your genetic makeup.
Understanding Your DPD Gene Test
The DPD (dihydropyrimidine dehydrogenase) enzyme is essential for breaking down 5-FU chemotherapy drugs. When genetic mutations affect this enzyme, your body cannot properly process the medication, leading to dangerously high drug levels and severe toxicity.
Our advanced PCR testing detects these genetic variations, giving your oncologist vital information to adjust your dosage or choose alternative treatments that are safer for your specific genetic profile.
Who Should Take This Test?
This test is especially important if you:
- Are scheduled to receive 5-FU chemotherapy for colorectal, breast, or other cancers
- Have a family history of severe reactions to chemotherapy
- Want to minimize treatment complications and hospital stays
- Seek personalized cancer treatment based on your genetic makeup
- Value proactive health management and treatment safety
Early detection of DPD deficiency can prevent weeks of hospitalization and potentially life-threatening complications.
Why This Test Matters For Your Health
By identifying your genetic risk before treatment, you gain:
- Personalized Treatment: Your oncologist can adjust dosage or choose safer alternatives
- Reduced Toxicity Risk: Prevent severe side effects like neutropenia, diarrhea, and mucositis
- Better Treatment Outcomes: Avoid treatment delays and interruptions due to toxicity
- Peace of Mind: Know your treatment plan is optimized for your genetic profile
- Cost Savings: Prevent expensive hospitalizations from treatment complications
Understanding Your Test Results
Your results will clearly indicate whether you have DPD gene mutations that affect 5-FU metabolism. Our comprehensive report includes:
- Clear genetic mutation status (normal or variant detected)
- Detailed explanation of what the results mean for your treatment
- Recommendations for your healthcare provider
- Easy-to-understand language with medical guidance
Our genetic counsellors are available to help you and your doctor understand the results and make informed treatment decisions.
Affordable Protection For Your Health Journey
| Test Option | Price | Turnaround Time |
|---|---|---|
| DPD Gene Mutations Test | R3,300 (was R3,650) | 12-15 working days |
Consider this investment against potential hospital costs from severe toxicity – which can easily exceed R50,000 for extended care.
Why Trust Oracle Genomics?
- Nationwide Coverage: Available across South Africa including Johannesburg, Cape Town, Durban, and Pretoria
- Medical Expertise: Tests conducted by qualified professionals using advanced PCR technology
- Accuracy Guaranteed: Reliable results you can trust for critical treatment decisions
- Patient-Focused: Empathetic support throughout your testing journey
- Proven Track Record: Trusted by healthcare providers nationwide
Test Preparation & Sample Collection
Sample Required: 4 mL (2 mL minimum) whole blood in 1 Lavender top (EDTA) tube
Important: Ship refrigerated. DO NOT FREEZE.
Mandatory: Duly filled Genomics Clinical Information Requisition Form (Form 20) must accompany your sample.
Take Control of Your Treatment Safety Today
Don’t leave your chemotherapy safety to chance. Knowledge is power when facing cancer treatment.
Book your DPD Gene Test now and give your medical team the information they need to protect you from unnecessary treatment risks.
Available at medical facilities nationwide. Contact your healthcare provider or visit our website to schedule your test.
Your genetic profile could be the key to safer, more effective cancer treatment. Act now for peace of mind.

