FISH 17p TP53 Deletion Test: Your Key to Understanding Blood Cancer Genetics
When facing concerns about blood cancers or unexplained blood disorders, having clear genetic information can provide the certainty you need to move forward with confidence. The FISH 17p TP53 Deletion Test offers precisely that clarity – a sophisticated genetic analysis that helps your healthcare team understand the specific characteristics of your condition and plan the most effective treatment approach.
Understanding Your FISH 17p TP53 Deletion Test
The FISH (Fluorescence In Situ Hybridization) 17p TP53 Deletion Test is a specialised genetic test that examines chromosome 17 for abnormalities in the TP53 gene. This gene acts as your body’s natural tumour suppressor – it helps prevent cells from growing and dividing too rapidly or in an uncontrolled way. When this protective gene is deleted or damaged, it can significantly impact how certain blood cancers develop and respond to treatment.
Think of the TP53 gene as your body’s quality control manager for cell growth. When it’s functioning properly, it ensures cells grow and divide normally. When it’s missing or damaged, this quality control system breaks down, potentially leading to cancer development and affecting how well treatments work.
Who Should Consider This Test?
This test is particularly important if you or your loved one:
- Have been diagnosed with chronic lymphocytic leukaemia (CLL) or are undergoing evaluation for suspected CLL
- Are being assessed for multiple myeloma or other blood cancers
- Have shown resistance to standard cancer treatments
- Need genetic information to guide personalised treatment decisions
- Have family history of blood cancers and want comprehensive assessment
- Are experiencing unexplained fatigue, frequent infections, or abnormal bleeding
Many South African patients find this test provides the missing piece in their diagnostic puzzle, helping their oncologists create targeted treatment plans that address their specific genetic profile.
Why This Test Matters for Your Health Journey
Understanding your TP53 status can significantly impact your treatment outcomes and quality of life:
- Personalised Treatment Planning: Results help your doctor choose treatments that are most likely to be effective for your specific genetic profile
- Early Intervention: Identifies high-risk features that may require more aggressive or alternative treatment approaches
- Treatment Response Prediction: Helps predict how well you might respond to certain chemotherapy drugs
- Prognostic Information: Provides valuable information about disease progression and long-term outlook
- Peace of Mind: Reduces uncertainty by providing clear, actionable genetic information
For many patients, this test represents a turning point in their cancer journey – moving from uncertainty to a clear, evidence-based treatment path.
Understanding Your Test Results
We understand that waiting for genetic test results can be anxiety-provoking. At Oracle Genomics, we provide clear, comprehensive reports that your healthcare team will explain in detail:
- Normal Result: No TP53 deletion detected – your tumour suppressor gene is intact
- Abnormal Result: TP53 deletion detected – this information helps guide specific treatment decisions
- Comprehensive Reporting: Your report includes detailed explanations and clinical implications
- Expert Consultation: Your results are best interpreted by your oncologist in the context of your overall health
Remember, genetic information is powerful – it provides your medical team with the insights needed to create the most effective treatment strategy for your unique situation.
Affordable, Accessible Genetic Testing
| Test Option | Price | Turnaround Time |
|---|---|---|
| Standard FISH 17p TP53 Deletion Test | ZAR 3,200 | 4 business days |
| Special Offer – Limited Time | ZAR 2,200 | 4 business days |
Save ZAR 1,000 on this essential genetic test. This special pricing makes advanced cancer genetics accessible to more South African patients.
Why Trust Oracle Genomics?
As South Africa’s leading genetic testing provider, we’re committed to your health and peace of mind:
- Nationwide Coverage: Convenient testing locations in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Accuracy: Our advanced FISH technology provides reliable, precise results you can trust
- Fast Results: Sample processing daily by 4 PM with results in just 4 business days
- Professional Expertise: Working closely with South Africa’s top oncologists and healthcare providers
- Patient-Centred Care: We understand the emotional journey of genetic testing and provide compassionate support
Sample Requirements
To ensure accurate results, please note:
- Sample Type: 5 mL (3 mL minimum) whole blood OR 4 mL (2 mL minimum) Bone Marrow
- Collection Tubes: 2 Green Top (Sodium Heparin) tubes
- Shipping: Maintain temperature at 18-22°C. DO NOT FREEZE
- Required Documentation: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory
Your healthcare provider will coordinate sample collection and ensure all requirements are met for optimal testing conditions.
Take Control of Your Health Journey Today
Don’t let uncertainty about your genetic profile delay your treatment decisions. The FISH 17p TP53 Deletion Test provides the clarity you and your medical team need to move forward with confidence.
Act Now: Early genetic information can make a significant difference in your treatment outcomes. Take the first step toward personalised cancer care by scheduling your FISH 17p TP53 Deletion Test today.
Special pricing of ZAR 2,200 available for limited time only. Don’t miss this opportunity to access advanced genetic testing at an affordable price.

