Understanding Your Cancer at the Genetic Level
When facing a cancer diagnosis, understanding the specific genetic drivers of your condition can be the key to more effective treatment. The NTRK2 Gene Rearrangement FISH Test provides this crucial insight, helping you and your oncologist make informed decisions about targeted therapy options.
What This Test Detects
The NTRK2 Gene Rearrangement Test uses Fluorescence In Situ Hybridization (FISH) technology to identify specific genetic abnormalities in the NTRK2 gene. When this gene becomes rearranged, it can drive uncontrolled cancer growth. Detecting these rearrangements is essential because they make cancers potentially responsive to targeted therapies called TRK inhibitors.
This advanced testing looks for fusion events where the NTRK2 gene partners with other genes, creating abnormal proteins that fuel cancer progression. Understanding these genetic changes helps your medical team determine if you’re a candidate for treatments that specifically target these abnormalities.
Who Should Consider This Test
This test is particularly important for patients with:
- Various solid tumour types including salivary gland, thyroid, and soft tissue cancers
- Cancers where standard treatments haven’t been effective
- Rare tumour types where NTRK fusions are more common
- Patients seeking targeted therapy options beyond conventional chemotherapy
- Those wanting to understand the genetic drivers of their specific cancer
If your oncologist has mentioned the possibility of targeted therapy or if you have a rare cancer type, this test could provide valuable treatment guidance.
Why This Matters for Your Treatment Journey
Getting this test can significantly impact your cancer treatment in several ways:
- Personalised Treatment: Identifies whether you may benefit from targeted TRK inhibitor therapies
- Informed Decisions: Provides crucial information for you and your doctor to choose the most appropriate treatment
- Potential for Better Outcomes: Targeted therapies often have fewer side effects and can be more effective for specific genetic profiles
- Peace of Mind: Knowing the genetic characteristics of your cancer reduces uncertainty about treatment options
- Future Planning: Results can inform long-term treatment strategies and monitoring approaches
Understanding Your Results
Your test results will clearly indicate whether NTRK2 gene rearrangements are present. A positive result means targeted TRK inhibitor therapies may be effective for your specific cancer type. A negative result helps rule out this particular genetic abnormality, allowing your medical team to explore other treatment avenues.
Our genetic specialists provide clear, understandable reports that your oncologist will discuss with you in detail. We ensure you have the support and explanation needed to understand what your results mean for your treatment journey.
Transparent Pricing for Peace of Mind
| Test Option | Price | Turnaround Time |
|---|---|---|
| Standard NTRK2 Gene Rearrangement Test | ZAR 2,600 | 4 Working Days |
| Special Offer Price | ZAR 2,350 | 4 Working Days |
Considering the potential impact on treatment effectiveness and quality of life, this test represents excellent value in your cancer care journey.
Why Trust Oracle Genomics
- Nationwide Coverage: Serving patients across South Africa including Johannesburg, Cape Town, Durban, and Pretoria
- Expert Accuracy: Using advanced FISH technology for reliable, precise results
- Quick Turnaround: Results typically available within 4 working days
- Professional Expertise: Working closely with oncologists and genetic specialists
- Patient-Focused: Clear communication and support throughout the testing process
Sample Requirements
To ensure accurate testing, please provide:
- Formalin fixed paraffin embedded tissue block OR three 4 micron sections on Poly L Lysine coated slides
- Ship at room temperature
- Completed Genomics Clinical Information Requisition Form (Form 20) – mandatory
Your healthcare provider will assist with sample collection and submission.
Take Control of Your Cancer Treatment Today
Don’t leave your treatment options to chance. Understanding your cancer’s genetic profile could open doors to more effective, targeted therapies with potentially better outcomes and fewer side effects.
Contact your oncologist today to discuss whether the NTRK2 Gene Rearrangement Test is right for you, or call Oracle Genomics to learn more about this vital genetic testing option.
Available to patients throughout South Africa with convenient sample collection points in major cities including Johannesburg, Cape Town, Durban, and Pretoria.
