Understanding Your Cancer at the Genetic Level
When facing a cancer diagnosis, understanding the specific genetic makeup of your tumour can be the key to finding the most effective treatment. The NTRK3 Gene Rearrangement FISH Test provides this crucial insight, helping you and your oncologist make informed decisions about targeted therapy options.
What Does This Test Detect?
The NTRK3 Gene Rearrangement Test uses advanced FISH (Fluorescence In Situ Hybridisation) technology to identify specific genetic rearrangements in the NTRK3 gene. These rearrangements can drive cancer growth and are found in various tumour types, including certain sarcomas, thyroid cancers, and other rare cancers.
When NTRK genes become rearranged, they can create fusion proteins that constantly signal cancer cells to grow and divide. Identifying these rearrangements is crucial because they can be targeted with specific medications called TRK inhibitors.
Who Should Consider This Test?
This test is particularly important for patients with:
- Advanced or metastatic cancers where standard treatments haven’t been effective
- Rare cancer types including certain sarcomas, thyroid cancers, or salivary gland tumours
- Paediatric cancers where NTRK rearrangements are more common
- Cancers of unknown primary origin
- Patients seeking personalised treatment options beyond conventional chemotherapy
If your oncologist has mentioned targeted therapy or if you’re exploring all available treatment options, this test could provide valuable information.
Why This Matters for Your Health Journey
Early identification of NTRK3 gene rearrangements can significantly impact your treatment outcomes:
- Targeted Treatment Options: Positive results may qualify you for TRK inhibitor therapies that specifically target the genetic driver of your cancer
- Reduced Side Effects: Targeted therapies often have fewer side effects compared to traditional chemotherapy
- Personalised Approach: Results help create a treatment plan tailored to your specific cancer genetics
- Peace of Mind: Knowing all available options have been explored reduces treatment uncertainty
- Better Outcomes: Patients with NTRK-positive cancers often respond well to targeted therapies
Understanding Your Results
We know waiting for test results can be anxiety-provoking. Our team provides clear, comprehensive reports that your oncologist will discuss with you:
- Positive Result: Indicates NTRK3 gene rearrangement is present, opening doors to targeted therapy options
- Negative Result: No rearrangement detected, helping focus on other treatment strategies
- Expert Interpretation: Our genetic specialists provide detailed analysis and context
- Quick Turnaround: Results typically available within 4 working days
Your results will be presented in clear language with guidance on next steps, ensuring you feel supported throughout your journey.
Transparent Pricing & Value
| Service | Regular Price | Special Price | Turnaround Time |
|---|---|---|---|
| NTRK3 Gene Rearrangement FISH Test | ZAR 2,350 | 4 Working Days |
Considering the potential impact on treatment decisions and outcomes, this test represents excellent value in your cancer care journey.
Why Trust Oracle Genomics?
We understand the importance of accuracy and reliability in genetic testing:
- Nationwide Coverage: Available across South Africa including Johannesburg, Cape Town, Durban, and Pretoria
- Expert Analysis: Our team includes experienced genetic specialists and oncologists
- Advanced Technology: Using FISH methodology for highest accuracy
- Patient-Focused: Clear communication and support throughout the process
- Medical Authority: Trusted by oncologists nationwide
Sample Requirements
To ensure accurate results, please provide:
- Formalin fixed paraffin embedded tissue block OR three 4 micron sections on Poly L Lysine coated slides
- Ship at room temperature
- Completed Genomics Clinical Information Requisition Form (Form 20) – mandatory
Sample submission daily by 6 pm for processing
Take Control of Your Cancer Treatment Today
Don’t leave treatment options unexplored. Early genetic testing can make a significant difference in your cancer journey.
Limited Time Offer: Save ZAR 250 on this essential genetic test. Take action today to explore all your treatment possibilities.
