FISH – RARA (17q21) Variant Translocation Test: Your Path to Precise Leukaemia Diagnosis
When facing concerns about blood disorders or leukaemia, having clear answers can make all the difference. The FISH – RARA (17q21) Variant Translocation Test provides the definitive genetic information needed for accurate diagnosis and proper treatment planning. We understand the anxiety that comes with waiting for answers, which is why we’ve made this advanced testing accessible and affordable across South Africa.
Understanding Your FISH RARA Translocation Test
The FISH (Fluorescence In Situ Hybridization) RARA test is a sophisticated molecular diagnostic tool that specifically detects abnormalities in the RARA gene located on chromosome 17. This test identifies translocations involving the RARA gene, which are critical markers for acute promyelocytic leukaemia (APL) – a specific type of acute myeloid leukaemia.
Using advanced fluorescence technology, our expert technicians can visualize and identify these genetic changes with exceptional precision, providing your healthcare team with the information needed to make informed treatment decisions.
Who Should Consider This Important Test?
This test is particularly important if you or your loved one are experiencing:
- Unexplained bleeding or bruising tendencies
- Persistent fatigue and weakness that doesn’t improve with rest
- Recurrent infections or fever without clear cause
- Abnormal blood cell counts identified in routine testing
- Suspected acute promyelocytic leukaemia based on clinical presentation
- Need for monitoring treatment response in confirmed APL cases
If your doctor has mentioned concerns about blood disorders or recommended genetic testing for leukaemia diagnosis, this test provides the clarity needed for proper medical management.
Why This Test Matters for Your Health Journey
Early and accurate detection of RARA translocations can significantly impact your treatment outcomes:
- Precise Diagnosis: Confirms or rules out specific leukaemia subtypes
- Targeted Treatment: Guides appropriate therapy selection, including all-trans retinoic acid (ATRA) treatment
- Treatment Monitoring: Helps track response to therapy over time
- Peace of Mind: Provides definitive answers to reduce uncertainty
- Better Outcomes: Early detection leads to more effective treatment strategies
Understanding Your Test Results
We know waiting for results can be stressful. Our team provides clear, comprehensive reports that your doctor will discuss with you:
- Positive Result: Indicates the presence of RARA translocation, confirming APL diagnosis and guiding specific treatment approaches
- Negative Result: Rules out this specific genetic abnormality, helping narrow down other potential diagnoses
- Expert Interpretation: Every report includes professional analysis from our experienced haematology specialists
- Follow-up Guidance: Clear next steps and recommendations for your healthcare journey
Remember, our genetic counsellors and medical team are available to help you understand your results and what they mean for your health.
Affordable, Accessible Testing for South Africans
| Service | Regular Price | Special Price | Value Saving |
|---|---|---|---|
| FISH – RARA (17q21) Variant Translocation Test | ZAR 2,000 | ZAR 500 Saving |
Turnaround Time: Sample accepted daily until 4 PM | Results in 4 working days
Sample Requirements: 5 mL (3 mL minimum) whole blood OR 4 mL (2 mL minimum) Bone Marrow from 2 Green Top (Sodium Heparin) tubes
Important: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory for processing
Why Trust Oracle Genomics?
- Nationwide Coverage: Accessible testing centres across South Africa including Johannesburg, Cape Town, Durban, and Pretoria
- Expert Team: Specialist haematologists and oncologists overseeing testing protocols
- Advanced Technology: State-of-the-art FISH methodology for reliable results
- Fast Results: 4-day turnaround for timely medical decisions
- Confidential Service: Your privacy and dignity are always protected
- Quality Assurance: Rigorous quality control measures ensuring accuracy
Take Control of Your Health Today
Don’t let uncertainty about your health create unnecessary stress. Early detection through precise genetic testing can make a significant difference in your treatment journey.
Limited Time Offer: Special pricing of ZAR 2,000 available for immediate bookings. Regular price ZAR 2,500.
Convenient Locations: Available at medical centres throughout Johannesburg, Cape Town, Durban, Pretoria and nationwide.
Important: If you are experiencing severe symptoms such as uncontrolled bleeding, high fever, or extreme fatigue, please seek immediate medical attention at your nearest emergency department.
