Understanding Your Autoimmune Skin and Eye Concerns
When your body’s immune system mistakenly attacks your own skin, mouth, or eyes, it can be both painful and frightening. You might notice blisters that don’t heal, persistent mouth sores, or eye irritation that affects your daily life. Our Histopathology Direct Immunofluorescence (DIF) Skin Conjunctival Biopsy IgA Test is specifically designed to detect the autoimmune antibodies causing these symptoms, giving you the answers you need to move forward with confidence.
What This Test Detects
This specialised test identifies IgA antibodies deposited in your skin or conjunctival tissue, which are key markers for autoimmune blistering diseases. Using advanced cryoprocessing and fluorescence microscopy, we can visualise these antibody deposits directly in your tissue sample, providing clear evidence of autoimmune activity that standard tests might miss.
Who Should Consider This Test
If you’re experiencing any of these symptoms, this test could provide crucial answers:
- Unexplained skin blisters or erosions that don’t heal properly
- Persistent mouth sores or ulcers affecting eating and speaking
- Eye redness, irritation, or conjunctival scarring
- Itchy skin bumps or blisters that resemble herpes but test negative
- Skin fragility where minor trauma causes blisters or erosions
- Family history of autoimmune blistering diseases
Why Early Detection Matters for Your Health
Getting an accurate diagnosis early can significantly improve your treatment outcomes and quality of life. Conditions like pemphigus and pemphigoid can progress without proper treatment, leading to more extensive skin involvement and potential complications. This test provides the definitive evidence your dermatologist or ophthalmologist needs to start targeted treatment, potentially preventing disease progression and reducing long-term damage to your skin and eyes.
Understanding Your Results with Confidence
Your results will clearly indicate whether IgA antibody deposits are present in your tissue sample. A positive result confirms autoimmune activity, while a negative result helps rule out these specific conditions. Our medical team provides clear explanations of your findings, and we recommend discussing results with your specialist who can interpret them in the context of your overall clinical picture.
Transparent Pricing and Value
| Test Description | Regular Price | Special Price |
|---|---|---|
| Histopathology DIF Skin Conjunctival Biopsy IgA Test | ZAR 250 | ZAR 250 |
Considering the potential costs of misdiagnosis or delayed treatment, this ZAR 250 investment in your health provides exceptional value and peace of mind.
Nationwide Trust and Accessibility
Oracle Genomics serves patients across South Africa, with convenient testing available in Johannesburg, Cape Town, Durban, Pretoria, and nationwide. Our network of dermatologists and ophthalmologists can perform the necessary biopsy, and we provide clear instructions for sample collection and transport to ensure optimal results.
Take Control of Your Health Today
Don’t let uncertainty about your skin or eye symptoms continue to affect your quality of life. With fast 4-working-day turnaround and the expertise of South Africa’s leading medical laboratory, you can get the answers you need to move forward with confidence. Contact your healthcare provider to arrange your biopsy, or reach out to our team for guidance on next steps.
Sample Requirements: Submit skin or conjunctival biopsy specimen in buffered normal saline. Biopsy should measure minimum 3mm. Ship refrigerated. Please provide brief clinical history.
Turnaround Time: Sample daily by 6pm | Report in 4 working days

