Direct Immuno-Fluorescence (DIF) Skin and Conjunctival Biopsy IgG Test

R250

When you’re experiencing unexplained skin rashes, blisters, or eye inflammation, getting the right diagnosis can feel overwhelming. Our Direct Immuno-Fluorescence (DIF) Skin and Conjunctival Biopsy IgG Test provides the clarity you need for autoimmune conditions affecting your skin and eyes. For just ZAR 250, this specialised test detects IgG antibody deposits that help diagnose conditions like pemphigus, pemphigoid, and other autoimmune blistering diseases. With results in just 4 working days, you’ll have the answers needed to start appropriate treatment. Our advanced cryoprocessing and fluorescence microscopy techniques ensure the highest accuracy, giving you and your healthcare provider confidence in your diagnosis. Available nationwide across South Africa, including Johannesburg, Cape Town, and Durban, we’re here to support your journey to better health with trusted, reliable testing.

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DIF Skin & Conjunctival Biopsy IgG Test | ZAR 250 | Autoimmune Diagnosis South Africa
Direct Immuno-Fluorescence (DIF) Skin and Conjunctival Biopsy IgG Test
R250

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Find Clarity for Your Skin and Eye Health Concerns

When unexplained skin rashes, painful blisters, or persistent eye inflammation disrupt your life, it’s natural to feel anxious and uncertain. You deserve answers, and our Direct Immuno-Fluorescence (DIF) Skin and Conjunctival Biopsy IgG Test provides the precise diagnostic information needed to understand what’s happening with your body’s immune response.

Understanding Your DIF IgG Test

This specialised test examines small tissue samples from your skin or the delicate conjunctival tissue around your eyes to detect IgG antibody deposits. Think of it as a detective looking for specific immune system markers that shouldn’t be there – these markers help identify autoimmune conditions where your body’s defence system mistakenly attacks healthy tissues.

Using advanced cryoprocessing and fluorescence microscopy, we can visualise these antibody patterns with exceptional clarity, providing your dermatologist or ophthalmologist with crucial diagnostic information.

Who Should Consider This Test?

This test is particularly important if you’re experiencing:

  • Unexplained skin blisters or erosions that don’t heal normally
  • Persistent skin rashes with itching or burning sensations
  • Eye redness, irritation, or inflammation that doesn’t respond to standard treatments
  • Symptoms suggesting autoimmune blistering diseases like pemphigus or pemphigoid
  • Mouth sores or genital lesions alongside skin symptoms
  • Family history of autoimmune conditions affecting skin or eyes

Many South Africans initially dismiss these symptoms as minor irritations, but early detection can prevent more serious complications and guide effective treatment.

Why This Test Matters for Your Health

Getting an accurate diagnosis is the first step toward effective treatment and peace of mind. This test helps:

  • Confirm or rule out specific autoimmune conditions – ending the uncertainty about your symptoms
  • Guide appropriate treatment plans – ensuring you receive the right medications from the start
  • Prevent disease progression – early intervention can protect your skin and vision
  • Reduce unnecessary treatments – avoiding medications that won’t help your specific condition
  • Provide psychological relief – knowing exactly what you’re dealing with reduces stress and anxiety

Understanding Your Test Results

We know waiting for results can be stressful, which is why we provide clear, comprehensive reports within 4 working days. Your results will show:

  • Presence or absence of IgG antibody deposits in your tissue
  • Patterns that help differentiate between various autoimmune conditions
  • Clear interpretation guidance for your healthcare provider

Your dermatologist or ophthalmologist will explain what these findings mean for your specific situation and discuss the most appropriate next steps for your care.

Transparent Pricing – No Hidden Costs

Test Description Regular Price Special Price Turnaround Time
Direct Immuno-Fluorescence (DIF) Skin and Conjunctival Biopsy IgG Test ZAR 250 ZAR 250 4 Working Days

Considering the potential costs of misdiagnosis or delayed treatment, this test represents excellent value for your health investment.

Why Trust Oracle Genomics?

  • Nationwide Coverage – Available across South Africa, including Johannesburg, Cape Town, Durban, and Pretoria
  • Expert Specialisation – Working closely with dermatologists and ophthalmologists
  • Advanced Technology – State-of-the-art cryoprocessing and fluorescence microscopy
  • Rapid Results – Samples processed daily by 6 PM, reports in 4 working days
  • Patient-Focused Care – We understand the anxiety around autoimmune diagnoses

Sample Requirements

To ensure accurate results, please provide:

  • Skin or conjunctival biopsy specimen in buffered normal saline
  • Minimum biopsy size of 3mm
  • Ship refrigerated to maintain sample integrity
  • Brief clinical history to help with interpretation

Your healthcare provider will perform the biopsy procedure and prepare the sample according to these specifications.

Take Control of Your Health Today

Don’t let uncertainty about your skin or eye symptoms continue to cause worry. Early diagnosis leads to better outcomes and peace of mind.



Limited availability – Secure your test slot while we have capacity. Our team is ready to support you through this diagnostic journey with compassion and expertise.