HLA-DR (Class II) Typing: Your Essential Guide to Successful Organ Transplantation
When facing the possibility of an organ transplant, the uncertainty can feel overwhelming. The HLA-DR (Class II) Typing Test provides the crucial genetic information needed to match donors and recipients accurately, significantly increasing the chances of transplant success and reducing rejection risks. This specialised testing brings clarity and confidence to one of life’s most challenging medical journeys.
Understanding HLA-DR Typing: The Science Behind Successful Transplants
HLA-DR (Human Leukocyte Antigen – DR) is part of your immune system’s recognition system. These proteins help your body distinguish between its own cells and foreign invaders. In transplantation, matching HLA-DR types between donor and recipient is critical because mismatches can trigger immune rejection of the transplanted organ.
Our advanced Reverse SSOP – Luminex methodology provides highly precise detection of HLA-DR antigens, giving your medical team the detailed genetic information needed to make informed decisions about your transplant compatibility.
Who Needs HLA-DR Typing? Critical Scenarios for South African Patients
- Kidney transplant candidates – Essential for matching living donors or deceased donor organs
- Liver transplant evaluation – Important for compatibility assessment
- Bone marrow transplantation – Critical for stem cell and bone marrow matching
- Pancreas transplant candidates – Required for comprehensive tissue typing
- Patients with potential living donors – Family members being evaluated as donors
- Transplant recipients on waiting lists – Required for national transplant registry
Why HLA-DR Matching Matters for Your Transplant Success
Proper HLA-DR matching significantly improves transplant outcomes by:
- Reducing rejection risk – Better matches mean lower chances of organ rejection
- Improving long-term survival – Well-matched transplants last longer
- Reducing medication needs – Better matches may require lower immunosuppressant doses
- Enhancing quality of life – Fewer complications and hospitalisations
- Providing peace of mind – Knowing your match is optimal reduces anxiety
Understanding Your HLA-DR Results: Clear Guidance for Patients
Your results will show specific HLA-DR types identified through our advanced testing. A perfect match means identical HLA-DR types between donor and recipient, while partial matches still enable successful transplantation with appropriate medical management. Your transplant team will explain what your specific results mean for your treatment plan and discuss any necessary adjustments to your care strategy.
Remember: Even partial matches can lead to successful transplants with modern medical protocols and careful monitoring.
Transparent Pricing for Essential Transplant Testing
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| HLA-DR (Class II) Typing Test | ZAR 3,250 | ZAR 2,900 | ZAR 350 |
Includes comprehensive analysis, detailed report, and professional interpretation
Why Trust Oracle Genomics for Your Transplant Testing?
- Nationwide Coverage – Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise – Working with leading nephrologists, hematologists, and transplant specialists
- Advanced Technology – State-of-the-art Reverse SSOP – Luminex methodology
- Rapid Turnaround – Results in 10-12 days to support timely medical decisions
- Patient-Focused Care – Empathetic support throughout your testing journey
Required Documentation for HLA-DR Testing
To ensure compliance with South African transplant regulations, please bring:
- Doctor’s prescription on letterhead
- 1 photograph each of recipient and donor (duly stamped)
- Consent form for HLA Typing for Solid Organ Transplant (Form 33)
- No special preparation required for the blood test
Take the Next Step Toward Your Transplant Journey
Don’t let uncertainty delay your path to better health. Our HLA-DR typing provides the critical information your medical team needs to plan your transplant with confidence.
Limited time special pricing available – Secure your essential transplant testing today and move forward with confidence in your medical journey.

