Understanding Your Brain Tumour Diagnosis: The IDH-1 Test That Could Change Your Treatment Journey
Facing a potential brain tumour diagnosis can feel overwhelming and frightening. We understand the uncertainty and anxiety that comes with neurological health concerns. The Immunohistochemistry Isocitrate Dehydrogenase (IDH-1) Test provides crucial clarity during this challenging time, offering specific genetic information that directly impacts your treatment options and prognosis.
What Does the IDH-1 Test Actually Detect?
This specialised test identifies mutations in the IDH-1 gene within tumour tissue. Think of it as reading the unique “fingerprint” of your specific tumour type. When this gene is mutated, it creates a distinct molecular signature that helps oncologists understand your tumour’s behaviour and predict how it might respond to different treatments.
Using advanced immunohistochemistry technology, we can precisely visualise whether the IDH-1 protein is present in its normal or mutated form. This isn’t just technical information – it’s knowledge that could significantly influence your treatment success and quality of life.
Who Should Consider This Critical Test?
This test is particularly important if you or your loved one:
- Have been diagnosed with or suspected of having a glioma brain tumour
- Are experiencing neurological symptoms like persistent headaches, seizures, or vision changes
- Need clarity on the most effective treatment approach for your specific tumour type
- Want to understand your long-term prognosis and treatment response likelihood
- Are working with an oncologist to develop a personalised treatment plan
Many patients find that knowing their IDH-1 status brings a sense of control and direction during an otherwise uncertain health journey.
Why This Knowledge Matters for Your Health Journey
The IDH-1 mutation status isn’t just technical data – it’s information that can:
- Guide Treatment Decisions: IDH-1 mutated tumours often respond differently to certain therapies, helping your medical team choose the most effective approach
- Predict Treatment Response: Understanding your mutation status helps anticipate how well specific treatments might work
- Provide Prognostic Information: IDH-1 mutated gliomas often have better long-term outcomes, offering hope and realistic expectations
- Enable Personalised Care: Move beyond one-size-fits-all treatment to approaches tailored to your specific tumour characteristics
- Reduce Treatment Uncertainty: Make informed decisions with greater confidence about your care pathway
Understanding Your Results: Clear Guidance for Peace of Mind
We know waiting for results can be anxiety-provoking. Here’s what to expect:
Positive for IDH-1 Mutation: This result typically indicates a glioma that may respond better to certain treatments and often has a more favourable prognosis. Your oncology team will use this information to tailor your treatment plan specifically to your tumour’s characteristics.
Negative for IDH-1 Mutation: This result helps rule out certain tumour types and guides your medical team toward other effective treatment strategies. It provides valuable information for determining the most appropriate care pathway.
Your results will be clearly explained in your report, and we recommend discussing them thoroughly with your oncologist to understand the specific implications for your situation.
Transparent Pricing – Investing in Your Health Clarity
| Service | Regular Price | Special Price |
|---|---|---|
| IDH-1 Mutation Test | R1,200 |
Considering the impact this test can have on your treatment success and quality of life, this represents exceptional value in personalised cancer care.
Why Trust Oracle Genomics With Your Critical Testing?
- Nationwide Accessibility: Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Rapid Turnaround: Results in 5-7 days depending on sample type
- Expert Collaboration: Working closely with oncologists and pathologists
- Advanced Methodology: Using proven immunohistochemistry techniques
- Patient-Centred Approach: We understand the emotional weight of neurological testing
Sample Requirements for Accurate Testing
To ensure the most accurate results, please provide:
- Tumour tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Ship at room temperature
- Include a copy of your histopathology report
- Provide biopsy site information and clinical history
Our team is available to guide you through the sample submission process if you have any questions.
Take the Next Step Toward Treatment Clarity
Don’t let uncertainty dictate your health journey. This R1,200 investment in diagnostic clarity could be the most important step you take toward effective, personalised treatment.
Book Your Test Today: Contact us to schedule your IDH-1 testing and take control of your neurological health with confidence and clarity.
Remember: Early, accurate diagnosis leads to more effective treatment planning and better health outcomes. Your journey to clearer understanding starts with this essential test.

