Protect Yourself from Severe Chemotherapy Side Effects
If you’re about to start 5-fluorouracil (5FU) chemotherapy, you deserve to know if you’re at risk for dangerous side effects before treatment begins. Many South African cancer patients experience unnecessary suffering because their genetic makeup makes them more sensitive to this common cancer drug. Our 5FU Toxicity Test gives you and your oncologist the information needed to create a safer, more effective treatment plan.
Understanding Your 5FU Toxicity Risk
5-fluorouracil is one of the most commonly used chemotherapy drugs in South Africa, but approximately 5-8% of patients have genetic variations that make them unable to properly process this medication. This can lead to severe, sometimes life-threatening side effects including:
- Severe diarrhoea and dehydration
- Dangerous mouth sores preventing eating
- Bone marrow suppression increasing infection risk
- Neurological complications
- Hospitalisation and treatment delays
Our test analyses your DPYD gene using advanced PCR and sequencing technology to identify if you carry genetic variations that increase your sensitivity to 5FU.
Who Should Take This Test?
This test is essential for any South African patient scheduled to receive 5FU chemotherapy for:
- Colorectal cancer
- Breast cancer
- Stomach cancer
- Pancreatic cancer
- Head and neck cancers
If you have a family history of severe reactions to chemotherapy or are concerned about treatment side effects, this test provides crucial information for your care team.
Why This Test Matters for Your Treatment
Knowing your genetic risk before starting 5FU chemotherapy can:
- Prevent severe side effects by allowing dose adjustments
- Reduce treatment interruptions that can compromise cancer control
- Lower hospitalisation risk and associated costs
- Provide peace of mind knowing your treatment is personalised
- Improve treatment outcomes through better tolerance
For ZAR 3,350, this test could save you from weeks of unnecessary suffering and potential medical complications.
Understanding Your Results
Your results will clearly indicate whether you have normal DPYD gene function or carry variations that increase your 5FU sensitivity. Our medical team provides:
- Clear, easy-to-understand report for you and your oncologist
- Interpretation of what your genetic results mean for your treatment
- Recommendations for discussing results with your healthcare team
- Support in understanding next steps
Remember: A positive result doesn’t mean you can’t receive 5FU treatment – it means your doctor can adjust your dose or consider alternative options for safer care.
Affordable Protection for Your Health
| Test | Regular Price | Special Price | Turnaround |
|---|---|---|---|
| 5FU Toxicity Genetic Test | ZAR 3,350 | 1 Week |
Consider this: The cost of one hospitalisation due to severe chemotherapy side effects can far exceed the price of this preventive test.
Why Trust Oracle Genomics?
- Nationwide Coverage: Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise: Specialised oncology genetic testing
- Accuracy Guaranteed: Advanced PCR and sequencing technology
- Quick Results: 1-week turnaround for timely treatment decisions
- Patient-Focused: Empathetic support throughout your journey
Simple Testing Process
Sample Required: 4 mL (2 mL minimum) whole blood from 1 Lavender Top (EDTA) tube
Important: Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Take Control of Your Cancer Treatment Today
Don’t wait until severe side effects disrupt your treatment and recovery. Get the genetic information you need to work with your oncologist for safer, more effective care.
Limited Time Offer: Special pricing of ZAR 3,350 available for immediate bookings. Secure your test before starting chemotherapy for optimal protection.

