Understanding AMBN Gene Amelogenesis Imperfecta Type 1F
If you’re worried about hereditary dental conditions affecting multiple family members, you’re not alone. Amelogenesis Imperfecta Type 1F is an inherited condition that affects tooth enamel development, often causing significant dental challenges across generations. At Oracle Genomics, we understand the emotional and physical burden this condition can place on families, and we’re here to provide clarity and hope through advanced genetic testing.
What This Test Detects
This specialised NGS genetic test specifically identifies mutations in the AMBN gene, which provides instructions for making ameloblastin – a crucial protein for proper enamel formation. When this gene contains mutations, it disrupts the normal development of tooth enamel, leading to the characteristic features of Amelogenesis Imperfecta Type 1F.
Who Should Consider This Test
This test is particularly important if you or family members experience:
- Family history of severe dental enamel problems
- Teeth that appear yellow, brown, or grey
- Enamel that chips, cracks, or wears down easily
- Increased tooth sensitivity to temperature changes
- Multiple family members requiring extensive dental work
- Children showing early signs of enamel development issues
Why Early Detection Matters for Your Family’s Health
Identifying AMBN gene mutations early provides significant advantages:
- Proactive Dental Planning: Early diagnosis allows for timely dental interventions and preventive care
- Family Planning Guidance: Understand inheritance patterns for future family planning decisions
- Reduced Dental Complications: Prevent severe dental issues through early management
- Peace of Mind: Eliminate uncertainty about the genetic cause of dental concerns
- Cost Savings: Early intervention can reduce long-term dental treatment expenses
Understanding Your Results
Our comprehensive genetic counselling ensures you fully understand your test results. We provide:
- Clear explanation of positive or negative results
- Detailed discussion of inheritance patterns
- Personalised recommendations for dental care
- Family member testing guidance if needed
- Ongoing support for result interpretation
Transparent Pricing & Value
| Service | Regular Price | Special Price |
|---|---|---|
| AMBN Gene Test | ZAR 9,350 | ZAR 6,700 |
| Genetic Counselling | Included | |
| Family Pedigree Analysis | Included | |
| Results Interpretation | Included | |
Nationwide Accessibility
We serve patients across South Africa with convenient testing locations in:
- Johannesburg and surrounding areas
- Cape Town and Western Cape region
- Durban and KwaZulu-Natal
- Pretoria and Gauteng province
- Plus nationwide coverage through our partner network
Take Control of Your Family’s Dental Health Today
Don’t let uncertainty about hereditary dental conditions continue to affect your family’s quality of life. Our AMBN Gene Amelogenesis Imperfecta Type 1F test provides the answers you need to make informed health decisions.
Book your test now and receive:
- Comprehensive genetic analysis using advanced NGS technology
- Professional genetic counselling session
- Family pedigree chart development
- Clear, actionable results in 3-4 weeks
- Ongoing support from our medical team
Ready to get answers? Contact Oracle Genomics today to schedule your test and take the first step toward understanding your family’s genetic dental health.
