Find Answers for Unexplained Kidney Problems with CLCN5 Gene Testing
Living with unexplained protein in your urine or recurrent kidney stones can be frightening and confusing. You may have visited multiple doctors, tried various treatments, but still lack clear answers about what’s causing your kidney issues. Our CLCN5 Gene Proteinuria with Hypercalciuric Nephrocalcinosis NGS Genetic DNA Test provides the definitive diagnosis you’ve been searching for, giving you and your family the clarity needed to move forward with confidence.
Understanding Your CLCN5 Genetic Test
The CLCN5 gene plays a crucial role in kidney function, specifically in the reabsorption of proteins and minerals. When this gene contains mutations, it can lead to Dent’s disease – a rare inherited condition characterized by low molecular weight proteinuria (protein in urine) and hypercalciuric nephrocalcinosis (excessive calcium in urine leading to kidney stones). Our advanced Next-Generation Sequencing (NGS) technology examines your DNA to identify any abnormalities in the CLCN5 gene with 99.9% accuracy.
This isn’t just another medical test – it’s a comprehensive genetic investigation that can explain years of unexplained symptoms and provide the foundation for targeted treatment strategies.
Who Should Consider This Genetic Test?
This test is specifically designed for individuals experiencing:
- Unexplained protein in urine (proteinuria) that doesn’t respond to standard treatments
- Recurrent kidney stones, especially if starting in childhood or young adulthood
- Family history of kidney disorders or kidney stones
- Elevated calcium levels in urine without clear cause
- Progressive kidney damage without typical risk factors like diabetes or hypertension
- Children with unexplained kidney problems or growth issues
If you’ve been told your kidney issues are “idiopathic” (without known cause) or if multiple family members have similar kidney problems, this test could provide the missing piece to your health puzzle.
Why Early Genetic Diagnosis Matters for Your Health
Getting an accurate CLCN5 gene diagnosis transforms your healthcare journey from uncertainty to clarity:
- Personalized Treatment Plans: Knowing the genetic cause allows your doctor to create targeted treatments rather than trial-and-error approaches
- Family Planning Guidance: Understand inheritance patterns and make informed decisions about family planning
- Prevent Progressive Damage: Early intervention can help preserve kidney function and prevent long-term complications
- Peace of Mind: End the diagnostic odyssey and finally understand what’s causing your symptoms
- Comprehensive Care: Connect with specialists who understand genetic kidney disorders
Many patients report feeling tremendous relief when they finally receive a definitive diagnosis after years of uncertainty.
Understanding Your Test Results
We understand that waiting for genetic test results can be anxiety-provoking. Our process is designed to provide clarity and support every step of the way:
- Clear, Understandable Reports: Your results will be explained in plain language with guidance on next steps
- Genetic Counselling Included: Every test includes professional genetic counselling to help you understand your results and their implications
- Family Pedigree Analysis: We’ll help map your family history to understand inheritance patterns
- Medical Team Coordination: We work with your existing healthcare providers to ensure seamless care integration
- Ongoing Support: Access to our genetic specialists for any follow-up questions
Whether your results show a CLCN5 mutation or rule it out, you’ll have the information needed to make informed healthcare decisions.
Transparent Pricing – Exceptional Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| CLCN5 Gene Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
| Genetic Counselling | INCLUDED | ||
| Family Pedigree Analysis | INCLUDED | ||
| Results Interpretation | INCLUDED | ||
Consider the cost of ongoing specialist visits, multiple tests, and potential complications without proper diagnosis. This single comprehensive test could save you thousands in unnecessary medical expenses.
Why Trust Oracle Genomics with Your Genetic Health?
- Nationwide Coverage: Convenient testing locations in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise: Our genetic specialists have years of experience in inherited kidney disorders
- Advanced Technology: State-of-the-art NGS technology ensures highest accuracy
- Patient-Centred Care: We understand the emotional journey of genetic testing
- Rapid Turnaround: Results within 3-4 weeks – faster than many international labs
- Multiple Sample Options: Blood draw, extracted DNA, or simple FTA card blood spot
Take the First Step Toward Clarity Today
Don’t let uncertainty about your kidney health continue to cause stress and anxiety. With our special pricing of only ZAR 6,700, there’s never been a better time to get the answers you deserve.
Limited Time Offer: This special pricing of ZAR 6,700 (regularly ZAR 9,350) is available for a limited time. Don’t delay getting the answers that could transform your kidney health management.
“After years of unexplained proteinuria and multiple specialist visits, the CLCN5 test finally gave us answers. The genetic counselling helped our entire family understand what was happening.” – Satisfied Patient, Cape Town
