Understanding Your Adrenal Health: Cortisol Stimulation Testing
Are you experiencing persistent fatigue that doesn’t improve with rest? Unexplained weight changes, mood swings, or feeling constantly overwhelmed? These could be signs of adrenal dysfunction affecting many South Africans. The Cortisol Stimulation by ACTH Test provides the answers you need to understand your body’s stress response system and take control of your health.
What This Test Reveals About Your Health
This specialised test evaluates how your adrenal glands respond to stimulation by measuring cortisol levels before and after receiving synthetic ACTH. Cortisol is your body’s primary stress hormone, and proper adrenal function is essential for energy regulation, metabolism, and stress management. The test involves drawing a fasting baseline blood sample, followed by administration of synthetic ACTH, with additional samples collected at 30 and 60 minutes to assess your adrenal response.
Who Should Consider This Test?
This test is particularly important if you experience:
- Persistent fatigue and low energy levels
- Unexplained weight loss or gain
- Difficulty handling stress
- Dizziness when standing up quickly
- Salt cravings and low blood pressure
- Muscle weakness and joint pain
- Mood changes, anxiety, or depression
- Skin hyperpigmentation or changes
If you have a family history of adrenal conditions or are being evaluated for Addison’s disease or Cushing’s syndrome, this test provides critical diagnostic information.
Why Early Detection Matters for Your Health
Identifying adrenal dysfunction early can prevent more serious health complications down the line. Proper diagnosis allows for:
- Targeted treatment plans that address the root cause
- Improved energy levels and quality of life
- Better stress management capabilities
- Prevention of adrenal crises in severe cases
- Peace of mind knowing your hormonal health status
Many patients report significant improvement in their symptoms once proper treatment begins, making this test a valuable investment in your long-term wellbeing.
Understanding Your Test Results
Your results will show how your cortisol levels change in response to ACTH stimulation. Normal responses indicate healthy adrenal function, while abnormal patterns may suggest:
- Primary adrenal insufficiency (Addison’s disease)
- Secondary adrenal insufficiency
- Adrenal fatigue or dysfunction
- Other hormonal imbalances
Our medical team will provide clear explanations of your results and, if needed, refer you to appropriate specialists for further evaluation and treatment. You won’t be left wondering what your numbers mean.
Affordable Health Screening Options
| Test Option | Price | Savings |
|---|---|---|
| Special Price | ZAR 650 | ZAR 100 off |
| Regular Price | ZAR 750 | – |
Considering the cost of untreated adrenal conditions and their impact on your quality of life, this test represents excellent value for comprehensive health insights.
Why Trust Oracle Genomics?
We understand that medical testing can feel overwhelming, which is why we’ve built our service around your comfort and confidence:
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Analysis: Results interpreted by qualified endocrinology specialists
- Fast Turnaround: Daily processing means you get answers quickly
- Patient-Focused Care: Empathetic support throughout your testing journey
- Accurate Methodology: Using advanced chemiluminescent immunoassay technology
Important Preparation Instructions
To ensure accurate results:
- Overnight fasting is mandatory before your test
- The test involves multiple blood draws at specific intervals
- Synthetic ACTH (Synacthen) will be administered during your appointment
- All samples are clearly marked with collection times for precise analysis
- Plan to spend approximately 2 hours at our facility for complete testing
Take the First Step Toward Better Health
Don’t let unexplained symptoms control your life. Understanding your adrenal health is the first step toward effective treatment and improved wellbeing. Our caring medical team is ready to help you get the answers you deserve.
Early detection leads to better outcomes. Book your Cortisol Stimulation Test today and take control of your hormonal health.

