Understanding Your Cortisol Levels: The High-Dose Dexamethasone Suppression Test
Are you experiencing unexplained weight gain, persistent fatigue, or mood swings that concern you? Many South Africans struggle with hormonal imbalances without realising the underlying cause could be cortisol-related. Our Cortisol Suppression by Dexamethasone Overnight High Dose Test provides the clarity you need to understand your body’s stress hormone regulation and take control of your health journey.
What This Test Reveals About Your Health
This specialised test evaluates how your body responds to a high dose of dexamethasone, a synthetic steroid. When administered properly, it helps determine if your adrenal glands are producing excessive cortisol – a condition that can significantly impact your quality of life. The test measures your cortisol levels before and after taking the medication, providing crucial insights into your endocrine system’s function.
Using advanced chemiluminescent immunoassay technology, we ensure the highest accuracy in measuring your cortisol response. This method is trusted by endocrinologists nationwide for its precision and reliability in diagnosing hormonal disorders.
Is This Test Right for You?
Consider this test if you’re experiencing:
- Unexplained weight gain, particularly around the abdomen and face
- Persistent high blood pressure that’s difficult to control
- Muscle weakness or fatigue that doesn’t improve with rest
- Mood changes, anxiety, or depression without clear cause
- Irregular menstrual cycles or fertility concerns
- Skin changes like thinning, bruising easily, or purple stretch marks
- High blood sugar levels or new-onset diabetes
If your doctor has mentioned possible Cushing’s syndrome or you have a family history of endocrine disorders, this test provides essential diagnostic information.
Why Early Detection Matters for Your Wellbeing
Identifying cortisol imbalances early can prevent serious complications including osteoporosis, diabetes, cardiovascular disease, and mental health challenges. Many patients report feeling relieved once they understand the root cause of their symptoms and can pursue targeted treatment.
Proper diagnosis leads to appropriate management strategies that can significantly improve your quality of life. Whether the results confirm Cushing’s syndrome or rule it out, you’ll have the information needed to make informed decisions about your healthcare.
Understanding Your Test Results
We understand that waiting for medical results can be anxiety-provoking. Our team provides clear, comprehensive explanations of your findings:
- Normal Suppression: Your cortisol levels decreased appropriately, suggesting normal adrenal function
- Incomplete Suppression: Your cortisol didn’t decrease as expected, indicating possible Cushing’s syndrome
- Guidance Provided: Regardless of results, we offer next-step recommendations and can coordinate with your healthcare provider
Remember: Abnormal results don’t automatically mean you have a serious condition – they provide valuable information for your doctor to develop the right treatment plan.
Affordable, Accessible Testing for South Africans
| Test Option | Price | Savings |
|---|---|---|
| Regular Price | ZAR 500 | – |
| Special Price | ZAR 450 | ZAR 50 savings |
Considering the potential health complications and healthcare costs associated with undiagnosed cortisol disorders, this test represents excellent value for your long-term wellbeing.
Why Trust Oracle Genomics?
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Oversight: Tests supervised by qualified endocrinology specialists
- Daily Turnaround: Quick results to reduce your waiting anxiety
- Proper Sample Handling: Strict protocols ensure sample integrity and accurate results
- Patient Education: Clear instructions and support throughout the testing process
Take the First Step Toward Understanding Your Health
Don’t let uncertainty about your symptoms continue to affect your quality of life. Early detection through proper testing can provide the answers you need and the peace of mind you deserve.
Ready to book your test? Contact us today to schedule your appointment at a convenient location near you. Our friendly staff will guide you through the preparation process and answer any questions you may have about the test procedure.
Important Preparation Note: Please inform us if you’re currently on steroid therapy, as this may affect test results. Fasting is required for the baseline sample, and specific timing instructions will be provided when you book.
Test Procedure Overview
Day 1: Fasting blood sample collected at 8:00 AM for baseline cortisol measurement. Take 4mg dexamethasone tablet orally at 11:00 PM.
Day 2: Second blood sample collected at 8:00 AM the following morning.
Both samples are carefully labelled with collection times and dates, then analysed using advanced laboratory methods to ensure accurate results.
