Find Peace of Mind with Advanced Melanoma Detection
When you notice a suspicious mole or skin lesion, the uncertainty can be overwhelming. The HMB-45 Immunohistochemistry Test provides the clarity you need to move forward with confidence. This specialised test is specifically designed to detect malignant melanoma – South Africa’s most aggressive form of skin cancer – giving you and your healthcare team the accurate information needed for proper diagnosis and treatment planning.
Understanding Your HMB-45 Test
The HMB-45 Immunohistochemistry Test works by detecting a specific protein called HMB-45 that’s found almost exclusively in melanoma cells. Using advanced laboratory techniques, our pathologists can identify this marker in your tissue sample, providing crucial evidence about whether a suspicious skin lesion is benign or malignant. This isn’t just another test – it’s a targeted investigation that looks for the specific fingerprints of melanoma cells.
Our method uses immunohistochemistry, a sophisticated technique that makes melanoma cells visible under the microscope using special stains. When melanoma is present, these cells light up with the HMB-45 marker, giving your doctor clear, definitive evidence to guide your treatment decisions.
Who Should Consider This Test?
This test is specifically recommended if you’re experiencing any of these concerns:
- You have a changing mole that’s growing, bleeding, or changing colour
- Your doctor has identified a suspicious skin lesion during examination
- You have a family history of melanoma or skin cancer
- You’ve had previous skin cancers and need ongoing monitoring
- You have fair skin and significant sun exposure history
- Your biopsy results are unclear and need further investigation
Many South Africans put off getting suspicious moles checked due to fear or uncertainty. Remember: early detection dramatically improves treatment outcomes and could save your life.
Why This Test Matters for Your Health
Getting the HMB-45 test provides multiple life-changing benefits:
- Early Detection: Catch melanoma at its most treatable stage
- Treatment Guidance: Help your doctor create the most effective treatment plan
- Peace of Mind: Replace uncertainty with clear, definitive answers
- Time Advantage: 5-day turnaround means faster treatment decisions
- Accuracy: 99% specificity for melanoma detection
- Cost Savings: Early detection prevents expensive late-stage treatments
For ZAR 1,000, you’re investing in potentially life-saving information that could prevent years of complicated treatment and emotional distress.
Understanding Your Results
We know waiting for test results can be stressful. Here’s what to expect:
Positive Result: If the test detects HMB-45 markers, it confirms melanoma presence. While this news may be concerning, remember that early detection gives you the best possible chance for successful treatment. Your doctor will discuss next steps and treatment options.
Negative Result: No HMB-45 markers detected means melanoma is unlikely. This provides valuable peace of mind and may help avoid unnecessary procedures.
Inconclusive Result: Rarely, additional testing might be needed. Our team will work closely with your doctor to ensure you get the answers you need.
Your results will include detailed explanations in clear language, and our medical team is available to answer any questions through your healthcare provider.
Transparent Pricing – No Surprises
| Service | Regular Price | Special Price |
|---|---|---|
| HMB-45 Immunohistochemistry Test | ZAR 1,500 | ZAR 1,000 |
This special pricing makes advanced melanoma detection accessible to more South Africans. Compared to the costs of late-stage cancer treatment, this test represents exceptional value for your health investment.
Why Trust Oracle Genomics?
We’ve built our reputation on accuracy, compassion, and accessibility:
- Nationwide Coverage: Serving patients in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Pathologists: Specialised oncologists and pathologists review every case
- Advanced Technology: State-of-the-art immunohistochemistry equipment
- Quick Turnaround: Results within 5 days for most samples
- Patient-Focused: Clear communication and compassionate care
- Medical Aid: We work with most major medical schemes
Take Control of Your Health Today
Don’t let uncertainty about a suspicious mole cause unnecessary stress and anxiety. Early detection could save your life, and the HMB-45 test provides the clarity you need to move forward with confidence.
Three Easy Ways to Get Started:
- Speak to your doctor about referring you for HMB-45 testing
- Contact us directly for guidance on the referral process
- Visit one of our nationwide collection centres
Remember: Melanoma detected early has a 99% survival rate. The small investment of ZAR 1,000 today could prevent life-threatening complications tomorrow.
Available in Johannesburg, Cape Town, Durban, Pretoria and nationwide. Same-day sample processing when received by 6pm.

