Understanding Your Dental Health: KLK4 Gene Amelogenesis Imperfecta Testing
If you or your family members struggle with dental enamel defects, discoloured teeth, or frequent dental problems, you’re not alone. Many South Africans face hereditary dental conditions that affect their confidence and quality of life. Our KLK4 Gene Amelogenesis Imperfecta Type 2A1 test provides the clarity you need to understand your genetic predisposition and take control of your dental health journey.
What This Test Reveals About Your Dental Health
The KLK4 gene plays a crucial role in enamel formation during tooth development. When mutations occur in this gene, it can lead to Amelogenesis Imperfecta Type 2A1 – a hereditary condition affecting tooth enamel quality and structure. Our advanced Next-Generation Sequencing (NGS) technology examines your KLK4 gene with 99.9% accuracy, identifying specific mutations that could be impacting your dental health.
This isn’t just about identifying a condition – it’s about understanding your body’s unique blueprint and making informed decisions about your dental care and treatment options.
Is This Test Right for You or Your Family?
Consider this test if you experience:
- Discoloured, yellow, or brown teeth despite good oral hygiene
- Thin, pitted, or grooved enamel surfaces
- Increased tooth sensitivity to hot, cold, or sweet foods
- Frequent dental cavities or enamel erosion
- Family history of similar dental conditions
- Children showing early signs of enamel development issues
Many South African families discover that their dental challenges have a genetic basis, providing relief and direction for proper treatment.
Why Early Detection Matters for Your Dental Future
Understanding your genetic predisposition to Amelogenesis Imperfecta offers significant benefits:
- Personalised Treatment Plans: Work with your dentist to create targeted dental care strategies
- Family Planning Insights: Understand inheritance patterns for future generations
- Preventive Care: Implement early interventions to protect remaining enamel
- Peace of Mind: Replace uncertainty with clear understanding and actionable information
- Cost Savings: Avoid unnecessary dental treatments by addressing the root cause
Understanding Your Test Results with Compassion
We know waiting for genetic test results can create anxiety. That’s why our process includes comprehensive genetic counselling both before and after testing. Your results will clearly indicate:
- Presence or absence of KLK4 gene mutations
- Specific type of mutation detected (if any)
- Inheritance pattern information for family planning
- Recommended next steps and specialist referrals
Our genetic counsellors will walk you through every detail, ensuring you feel supported and informed throughout your journey.
Transparent Pricing – Investing in Your Dental Health
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| KLK4 Gene Amelogenesis Test | ZAR 6,700 | ZAR 2,650 | |
| Genetic Counselling Session | Included at no extra cost | ||
| Family Pedigree Analysis | Included at no extra cost | ||
Consider this: The cost of ongoing dental treatments for undiagnosed Amelogenesis Imperfecta can far exceed the investment in genetic testing.
Why South Africans Trust Oracle Genomics
- Nationwide Coverage: Accessible testing in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Genetic Counselling: Comprehensive sessions to create family pedigree charts and explain inheritance patterns
- Advanced NGS Technology: 99.9% accuracy using cutting-edge genetic sequencing
- Quick Turnaround: Results within 3-4 weeks
- Multiple Sample Options: Blood, extracted DNA, or simple blood spot on FTA card
- Dermatology Specialists: Working with qualified medical professionals
Take the First Step Toward Dental Health Clarity
Don’t let uncertainty about your dental health continue to affect your confidence and quality of life. Our special pricing of ZAR 6,700 makes comprehensive genetic testing accessible to South African families.
Limited Time Offer: This special pricing of ZAR 6,700 (regularly ZAR 9,350) won’t last forever. Secure your testing today and gain the clarity you deserve about your dental health inheritance.
“After years of dental struggles, the KLK4 test gave our family the answers we needed. The genetic counselling was incredibly supportive.” – Thandi, Cape Town

