Understanding Your Hereditary Cancer Risk: MLH1 Gene Testing in South Africa
When cancer runs in your family, the uncertainty can feel overwhelming. You may wonder if you’re destined to follow the same path as your loved ones. The MLH1 Gene Mismatch Repair Cancer Syndrome NGS Genetic DNA Test provides the clarity and peace of mind you deserve. This comprehensive genetic test specifically examines the MLH1 gene, which plays a critical role in preventing certain types of cancer from developing.
What Does This Test Actually Detect?
The MLH1 gene is your body’s natural cancer protection system – it acts like a spell-checker for your DNA, catching and correcting errors before they can lead to cancer development. When this gene contains mutations, your risk for colorectal cancer, endometrial cancer, stomach cancer, and other related cancers increases significantly. Our advanced Next Generation Sequencing (NGS) technology examines every part of your MLH1 gene with exceptional accuracy, identifying even the smallest mutations that could impact your health.
Who Should Consider This Life-Changing Test?
This test is particularly important if you identify with any of these situations:
- Multiple family members diagnosed with colorectal, endometrial, or stomach cancer
- Cancer diagnosed at unusually young ages (before 50)
- Personal history of multiple different cancers
- Known MLH1 gene mutation in your family
- Unexplained gastrointestinal symptoms with family cancer history
- Planning for family and concerned about passing genetic risks to children
If you’re reading this and thinking “this sounds like my family,” you’ve taken the first important step toward understanding your genetic health.
Why This Knowledge Could Transform Your Health Journey
Understanding your MLH1 status provides more than just information – it gives you power:
- Early Detection Advantage: If you carry the mutation, you can begin targeted screening earlier and more frequently, catching potential cancers at their most treatable stages
- Family Protection: Your results can help other family members understand their own risks and take preventive action
- Peace of Mind: A negative result can relieve years of anxiety about your cancer risk
- Personalised Prevention: Positive results allow for customised screening and prevention strategies with your healthcare provider
- Reproductive Planning: Knowledge that can inform family planning decisions
Understanding Your Results: Clear Guidance, Not Confusion
We know waiting for genetic test results can be anxiety-provoking. That’s why we provide clear, comprehensive reports with expert interpretation:
- Positive Result: This means a mutation was found in your MLH1 gene. Our genetic counsellors will explain exactly what this means for your cancer risk and connect you with appropriate specialists for ongoing management
- Negative Result: No MLH1 mutation was detected, meaning you don’t carry the specific hereditary risk we tested for
- Uncertain Variant: Sometimes we find genetic changes where the cancer risk isn’t yet fully understood. We’ll explain what we know and provide guidance for monitoring
Regardless of your results, you’ll receive personalised recommendations for next steps and ongoing care.
Transparent Pricing – Investing in Your Health Future
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| MLH1 Gene NGS Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
What’s Included: Comprehensive genetic analysis, genetic counselling session, family pedigree chart creation, detailed results report, and post-test consultation guidance.
Consider this: The cost of comprehensive cancer treatment can exceed ZAR 500,000. This test represents a small investment that could potentially save both money and lives through early detection and prevention.
Why Thousands of South Africans Trust Oracle Genomics
- Nationwide Coverage: Accessible testing centres in Johannesburg, Cape Town, Durban, Pretoria and throughout South Africa
- Expert Genetic Counselling: Every test includes professional genetic counselling to ensure you fully understand your results and options
- Advanced NGS Technology: State-of-the-art sequencing for the most accurate results available
- Multiple Sample Options: Blood draw, extracted DNA, or simple finger-prick blood spot on FTA card
- Timely Results: Most results within 3-4 weeks
- Oncologist Partnership: Working closely with South Africa’s leading cancer specialists
Take the First Step Toward Genetic Clarity Today
Your family’s health history doesn’t have to dictate your future. With the MLH1 Gene Test, you gain the knowledge to make informed decisions about your health journey.
Limited Time Special: Save ZAR 2,650 on your genetic testing while this special pricing lasts
Convenient Booking: Multiple sample options make testing accessible no matter where you are in South Africa
Expert Support: From genetic counselling through to results interpretation, we’re with you every step of the way
Don’t let uncertainty about hereditary cancer risk control your life. Take the proactive step thousands of South African families have already taken toward genetic understanding and peace of mind.

