Find Answers for Unexplained Strokes and Neurological Symptoms
When strokes, severe migraines, or cognitive changes occur without clear cause, the uncertainty can be overwhelming. Our NOTCH3 Gene CADASIL NGS Genetic DNA Test offers clarity and direction for South African families affected by mysterious neurological symptoms. At Oracle Genomics, we understand the anxiety that comes with unexplained health challenges, which is why we’ve made this advanced genetic testing accessible and affordable across South Africa.
Understanding CADASIL Genetic Testing
CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a hereditary condition that affects small blood vessels in the brain. Our test specifically examines the NOTCH3 gene using Next-Generation Sequencing (NGS) technology – the most advanced method available. This isn’t just a test; it’s a pathway to understanding your genetic blueprint and preventing future health complications.
Who Should Consider This Test?
This test is particularly important if you or your family members experience:
- Recurrent strokes or mini-strokes (TIAs) before age 60
- Severe migraine headaches with aura
- Progressive cognitive decline or early dementia
- Mood changes, depression, or apathy
- Family history of similar neurological symptoms
- Unexplained white matter changes on brain MRI
If multiple family members have experienced these symptoms, genetic testing becomes even more crucial for early intervention.
Why Early Detection Matters for Your Health
Knowing your genetic status empowers you to:
- Prevent future strokes through targeted medical management
- Make informed family planning decisions
- Access appropriate treatments and monitoring
- Reduce anxiety through definitive answers
- Alert other family members who may be at risk
- Plan for the future with confidence and clarity
Early detection can significantly improve quality of life and prevent devastating neurological damage.
Understanding Your Test Results
We make understanding your results straightforward and reassuring:
- Positive Result: A NOTCH3 gene mutation is detected. Our genetic counsellors will explain what this means for your health and provide guidance on next steps
- Negative Result: No NOTCH3 mutation found. This provides peace of mind and helps rule out CADASIL as the cause of symptoms
- Uncertain Variant: Rarely, we may find a genetic change of uncertain significance. Our experts will explain what this means and recommend appropriate follow-up
Regardless of your results, you’ll receive comprehensive support and guidance from our medical team.
Affordable Genetic Testing for South Africans
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| NOTCH3 Gene CADASIL NGS Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
Includes genetic counselling session and comprehensive result interpretation
Why Trust Oracle Genomics?
- Nationwide Coverage: Available in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Expert Team: Board-certified geneticists and counsellors
- Advanced Technology: Latest NGS sequencing for maximum accuracy
- Quick Turnaround: Results in 3-4 weeks
- Multiple Sample Options: Blood, extracted DNA, or simple blood spot on FTA card
- Complete Support: From pre-test counselling to result interpretation
Take Control of Your Neurological Health Today
Don’t let uncertainty about your neurological symptoms control your life. Early detection through genetic testing can provide the answers you need to protect your health and your family’s future.
Limited Time Offer: Save ZAR 2,650 on your CADASIL genetic test. This special pricing won’t last forever.
Convenient Testing: Choose from multiple sample collection methods to suit your needs.
Your journey to clarity and peace of mind begins with a simple test. Contact Oracle Genomics today and take the first step toward understanding your genetic health.
