Take Control of Your Blood Health with Advanced Genetic Testing
When facing concerns about blood disorders or leukaemia, having clear, definitive answers can bring immense peace of mind. The PML-RARA Gene Rearrangement Test provides that clarity through cutting-edge molecular technology, specifically designed to detect Acute Promyelocytic Leukaemia – a condition that requires precise diagnosis for optimal treatment.
Understanding Your PML-RARA Gene Test
This specialised test detects a specific genetic abnormality where chromosomes 15 and 17 swap genetic material, creating what’s called the PML-RARA fusion gene. This rearrangement is the hallmark of Acute Promyelocytic Leukaemia (APL), and identifying it accurately is crucial because APL responds exceptionally well to targeted therapies when detected early.
Using Real-Time PCR technology, our test provides quantitative results that not only confirm the presence of this genetic change but also help monitor treatment response over time. This means your medical team can track how well your treatment is working and make adjustments as needed.
Who Should Consider This Important Test?
This test is particularly important if you’re experiencing:
- Unexplained bruising or bleeding tendencies
- Persistent fatigue and weakness
- Frequent infections or fever
- Bone pain or tenderness
- Abnormal blood test results suggesting leukaemia
- Family history of blood disorders
If your doctor has mentioned concerns about acute leukaemia or if you’re undergoing evaluation for blood abnormalities, this test provides the definitive answers needed for proper diagnosis and treatment planning.
Why This Test Matters for Your Health Journey
Early and accurate detection of the PML-RARA rearrangement can be life-changing because:
- Targeted Treatment: APL responds remarkably well to specific medications when identified correctly
- Treatment Monitoring: Quantitative results help track treatment effectiveness
- Peace of Mind: Clear answers reduce uncertainty and anxiety
- Better Outcomes: Early detection significantly improves survival rates
- Personalised Care: Results guide your medical team in creating the most effective treatment plan
Understanding Your Test Results
We understand that waiting for genetic test results can be stressful. Our process is designed to provide clarity and support:
- Positive Result: Indicates the presence of the PML-RARA rearrangement, confirming APL diagnosis and guiding targeted treatment
- Negative Result: Rules out this specific type of leukaemia, helping your doctor explore other possibilities
- Quantitative Data: Provides measurement levels that help monitor treatment response over time
Your results will be thoroughly explained by our medical team, and we’ll ensure you understand what they mean for your health journey.
Transparent Pricing for Peace of Mind
| Test Option | Regular Price | Special Price | Savings |
|---|---|---|---|
| PML-RARA Gene Rearrangement Quantitative PCR Test | ZAR 2,500 | ZAR 1,500 |
This special pricing represents exceptional value for advanced genetic testing that can significantly impact treatment decisions and outcomes.
Why Trust Oracle Genomics?
We’re committed to providing South Africans with access to world-class genetic testing:
- Nationwide Coverage: Serving patients across Johannesburg, Cape Town, Durban, Pretoria and throughout South Africa
- Expert Accuracy: State-of-the-art Real-Time PCR technology ensures reliable results
- Fast Turnaround: Sample collection Monday/Wednesday/Friday by 9am, with reports available Tuesday/Thursday/Saturday
- Professional Support: Our team includes experienced oncologists and genetic specialists
- Patient-Focused Care: We understand the emotional journey and provide compassionate support
Take the Next Step Toward Clarity
Don’t let uncertainty about your blood health create unnecessary stress. Early detection through accurate genetic testing can make all the difference in your treatment journey.
Convenient Nationwide Access: With collection centres across major cities including Johannesburg, Cape Town, Durban, and Pretoria, getting tested has never been easier. Take control of your health today with confidence and clarity.

