Find Answers for Unexplained Nerve Weakness and Numbness
Are you experiencing mysterious episodes of weakness, numbness, or temporary paralysis after something as simple as leaning on your elbow or crossing your legs? These frustrating symptoms might be Hereditary Neuropathy with Pressure Palsies (HNPP) – a genetic condition affecting thousands of South Africans without proper diagnosis. At Oracle Genomics, we understand how concerning these neurological symptoms can be, and we’re here to provide the clarity and answers you deserve through our advanced PMP22 Gene Neuropathy DNA test.
Understanding Your HNPP Genetic Test
The PMP22 Gene Neuropathy test specifically looks for deletions in the PMP22 gene, which is responsible for producing a protein essential for proper nerve function. When this gene is missing or altered, your nerves become more vulnerable to pressure damage, leading to the characteristic symptoms of HNPP. Our Next Generation Sequencing (NGS) technology examines your DNA with exceptional precision, ensuring we detect even the smallest genetic variations that could be causing your symptoms.
This isn’t just another blood test – it’s a comprehensive genetic investigation that provides definitive answers about whether you carry the hereditary predisposition to pressure-related nerve damage. The test requires only a simple blood sample or DNA extraction, making the process straightforward and minimally invasive.
Who Should Consider This Genetic Test?
This test is particularly important if you experience:
- Recurrent episodes of weakness or numbness in arms, hands, or legs
- Temporary paralysis after minor pressure on nerves (like leaning on elbows)
- Family history of similar neurological symptoms
- Unexplained foot drop or wrist drop
- Sensory changes that come and go without clear cause
- Difficulty with fine motor skills during symptom episodes
Many South Africans live with these symptoms for years without understanding their genetic origin. If you’ve been told your nerve issues are “just stress” or “unexplained,” this test can provide the concrete answers needed for proper management.
Why Early Detection Matters for Your Health
Knowing you have HNPP transforms how you manage your health. Instead of fearing the next episode of weakness, you can:
- Prevent future episodes by avoiding pressure points that trigger symptoms
- Receive proper diagnosis instead of being misdiagnosed with other conditions
- Make informed family planning decisions with genetic counselling guidance
- Access appropriate treatments and management strategies
- Reduce anxiety by understanding the cause of your symptoms
- Protect your nerves from permanent damage through early intervention
Early detection means you can take control of your neurological health rather than living in uncertainty.
Understanding Your Test Results
We know waiting for genetic test results can be anxiety-provoking. That’s why we provide comprehensive support throughout the process:
- Clear, understandable reports written in plain language
- Genetic counselling session included to explain your results
- Family implications guidance to help you understand inheritance patterns
- Management recommendations from neurological specialists
- Ongoing support for any questions about your results
Your results will clearly indicate whether the PMP22 gene deletion is present, and our genetic counsellors will help you understand exactly what this means for your health and your family.
Transparent Pricing – Exceptional Value
| Test Component | Regular Price | Special Price | Savings |
|---|---|---|---|
| PMP22 Gene Neuropathy (HNPP) NGS Test | ZAR 9,350 | ZAR 6,700 | ZAR 2,650 |
| Genetic Counselling Session | INCLUDED | ||
| Comprehensive Results Report | INCLUDED | ||
| Turnaround Time | 3-4 Weeks | ||
Considering the cost of repeated doctor visits, misdiagnoses, and ongoing symptom management, this test represents significant long-term health savings and peace of mind.
Why Trust Oracle Genomics?
- Nationwide Coverage: Convenient testing locations in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Neurological Expertise: Tests developed and interpreted by specialist neurologists
- Advanced Technology: Next Generation Sequencing ensures 99.9% accuracy
- Genetic Counselling Included: Professional guidance before and after testing
- Proven Track Record: Thousands of South Africans trust our genetic testing services
- Patient-Focused Approach: We understand the emotional journey of genetic testing
Take Control of Your Neurological Health Today
Don’t let unexplained nerve symptoms control your life any longer. With our special pricing of ZAR 6,700, there’s never been a better time to get the answers you need.
Urgent Note: Early detection of HNPP can prevent permanent nerve damage. Every day without diagnosis increases the risk of long-term complications. Book your test today and start your journey to better neurological health.

