TPMT Genotyping: Your Personalised Path to Medication Safety
Are you concerned about medication side effects or wondering why certain treatments don’t work as expected? Many South Africans face the uncertainty of medication reactions without understanding the genetic factors at play. The TPMT Genotyping test provides the clarity you need to ensure your medications work safely and effectively for your unique genetic makeup.
Understanding Your TPMT Genetic Profile
Thiopurine Methyltransferase (TPMT) is an enzyme your body produces to process certain medications safely. Your genetic code determines how efficiently this enzyme works. Our TPMT Genotyping test examines four key genetic variations (*2, *3A, *3B, *3C) that affect your ability to metabolise medications like azathioprine, mercaptopurine, and thioguanine – commonly used for autoimmune diseases, cancer treatments, and organ transplants.
Think of TPMT as your body’s natural medication processing system. Some people have highly efficient systems, while others process medications more slowly. Knowing your genetic profile helps your doctor prescribe the right medication at the correct dosage, preventing potentially serious side effects.
Who Should Consider TPMT Genotyping?
This test is particularly important if you:
- Are starting treatment for autoimmune conditions like Crohn’s disease, ulcerative colitis, or rheumatoid arthritis
- Require medication for certain types of cancer or leukaemia
- Have experienced unexpected side effects from previous medications
- Are preparing for organ transplant procedures
- Have family members who experienced severe medication reactions
- Want to ensure your treatment plan is personalised to your genetic profile
Many patients in Johannesburg, Cape Town, and Durban have discovered through this test why previous treatments caused unexpected complications.
Why TPMT Testing Matters for Your Health
Getting your TPMT genetic profile offers multiple life-changing benefits:
- Prevent Serious Side Effects: Avoid bone marrow suppression and other dangerous reactions
- Optimise Treatment Effectiveness: Ensure medications work as intended
- Personalised Dosing: Receive medication doses tailored to your genetic capacity
- Peace of Mind: Know your treatment plan is scientifically optimised for you
- Lifetime Value: Your genetic profile remains constant, providing guidance for future treatments
Patients across South Africa report significantly improved treatment experiences after understanding their TPMT status.
Understanding Your TPMT Test Results
Your results will fall into one of three categories, each with clear guidance:
- Normal Metaboliser: You can process medications normally – standard dosing is typically safe
- Intermediate Metaboliser: Your body processes medications more slowly – reduced dosing may be necessary
- Poor Metaboliser: Your body processes medications very slowly – alternative treatments or significantly reduced dosing is essential
Our genetic counsellors and healthcare professionals will explain your results in simple terms and provide clear recommendations for discussing findings with your doctor. Remember, this test provides valuable information, not a diagnosis.
Transparent Pricing – Exceptional Value
| Service | Regular Price | Special Price | Savings |
|---|---|---|---|
| TPMT Genotyping Test | ZAR 2,700 | ZAR 2,000 | ZAR 700 |
Turnaround Time: 5-7 days
Sample Required: Peripheral blood (EDTA Vacutainer 2ml)
Method: Sanger Sequencing (99.9% accuracy)
Consider this investment in your health: ZAR 2,000 could prevent hospitalisation costs and ensure your treatment works effectively from the start.
Why Trust Oracle Genomics?
We’re committed to providing South Africans with accessible, reliable genetic testing:
- Nationwide Coverage: Convenient testing locations in Johannesburg, Cape Town, Durban, Pretoria and across South Africa
- Medical Expertise: Tests conducted by qualified genetic specialists
- Accuracy Guarantee: Advanced Sanger Sequencing technology ensures precise results
- Patient Support: Clear result explanations and guidance for next steps
- Privacy Protection: Strict confidentiality of your genetic information
Note: This test requires a doctor’s prescription, except for surgery preparation, pregnancy planning, or international travel documentation.
Take Control of Your Medication Safety Today
Don’t leave your medication safety to chance. Understanding your TPMT genetic profile could be the difference between successful treatment and dangerous side effects.
Book Your TPMT Genotyping Test Now:
- Call our dedicated healthcare line for immediate assistance
- Visit our website to schedule your appointment online
- Consult with your doctor about obtaining a prescription
- Visit any of our nationwide collection centres
Thousands of South Africans have already taken this important step toward personalised healthcare. Join them in making informed decisions about your treatment journey.
Your genetic profile holds the key to safer, more effective medication. Unlock that knowledge with Oracle Genomics.
