TPMT Genotyping Test: Personalised Cancer Treatment for South African Patients
Starting cancer treatment can be overwhelming, but knowing your genetic profile can make all the difference. The TPMT Genotyping Test helps ensure your thiopurine medications work effectively while minimising dangerous side effects. For ZAR 2,400, gain the confidence that comes with personalised, safe treatment planning.
Understanding Your TPMT Genotyping Test
The TPMT (Thiopurine Methyl Transferase) enzyme plays a crucial role in how your body processes thiopurine medications like azathioprine, 6-mercaptopurine, and 6-thioguanine. These medications are commonly used to treat various cancers, autoimmune diseases, and inflammatory conditions.
Your genetic makeup determines how efficiently your body produces this enzyme. Some people have genetic variations that result in low or absent TPMT activity, which can lead to severe toxicity when taking standard doses of these medications. Our advanced Real Time PCR testing method accurately identifies your TPMT genotype, providing your healthcare team with essential information for safe treatment planning.
Who Should Take This TPMT Test?
This test is essential if you’re:
- Starting thiopurine therapy for cancer treatment
- Being treated for autoimmune conditions like Crohn’s disease or ulcerative colitis
- Experiencing unexpected side effects from current thiopurine medications
- Planning organ transplant and requiring immunosuppressive therapy
- Having a family history of adverse reactions to thiopurine drugs
Early testing can prevent weeks of unnecessary suffering and potential hospitalisation from medication toxicity.
Why TPMT Testing Matters for Your Health
Getting your TPMT genotype tested before starting treatment offers significant benefits:
- Prevent Severe Side Effects: Avoid bone marrow suppression, which can lead to life-threatening infections and bleeding
- Personalised Dosing: Receive medication doses tailored to your genetic profile for optimal effectiveness
- Reduce Treatment Delays: Minimise interruptions in your cancer therapy due to adverse reactions
- Cost Savings: Prevent expensive hospital stays and additional treatments for managing side effects
- Peace of Mind: Start your treatment journey with confidence, knowing your medications are safe for you
Understanding Your TPMT Test Results
Your results will fall into one of three categories, each with clear guidance for your treatment:
- Normal Metaboliser: You have normal TPMT activity and can typically take standard medication doses
- Intermediate Metaboliser: You have reduced enzyme activity and may require lower medication doses
- Poor Metaboliser: You have very low or absent enzyme activity and may need alternative medications or significantly reduced doses
Our detailed report includes easy-to-understand explanations and specific recommendations for your healthcare provider. We ensure you receive comprehensive support in interpreting your results.
TPMT Genotyping Test Pricing
| Test Description | Regular Price | Special Price | Savings |
|---|---|---|---|
| TPMT Genotyping Test | ZAR 2,400 | ZAR 600 |
This investment in personalised medicine can save thousands in potential hospital costs and prevent treatment complications.
Test Details & Process
- Turnaround Time: Sample Monday/Thursday by 11am; Results Wednesday/Saturday
- Sample Required: 4mL (2mL minimum) whole blood in 1 Lavender Top (EDTA) tube
- Shipping: Ship refrigerated. DO NOT FREEZE
- Mandatory: Duly filled Genomics Clinical Information Requisition Form (Form 20)
- Testing Method: Real Time PCR for maximum accuracy
Why Trust Oracle Genomics?
Oracle Genomics is committed to providing South African patients with world-class genetic testing services:
- Nationwide Coverage: Available throughout South Africa including Johannesburg, Cape Town, Durban, and Pretoria
- Medical Expertise: Specialised oncology testing with accurate, reliable results
- Patient-Focused Care: Empathetic support throughout your testing journey
- Fast Results: Quick turnaround to support timely treatment decisions
- Quality Assurance: Stringent quality controls ensuring test accuracy
Take Control of Your Treatment Today
Don’t leave your medication safety to chance. The TPMT Genotyping Test provides the genetic insight needed for safe, effective treatment. For only ZAR 2,400, you can avoid potentially dangerous side effects and ensure your therapy is tailored to your unique genetic profile.
Book your test now and start your treatment journey with confidence. Our team is ready to assist you with convenient testing options across South Africa.
Limited time special pricing – secure your personalised treatment plan today!
